Tan Lab | DSigDB

Gene Set: D4 : CTD - Carbaryl

Collection

D4 : CTD

Chemical Name

Carbaryl ( From PubChem : CARBARYL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
201.221 g/mol	1	3	2.9489	True

Structure

InChI

InChI=1S/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)

InChIKey

CVXBEEMKQHEXEN-UHFFFAOYSA-N

Links

Gene (25 / 67)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			ACHE		D012721
CTD	decreases(activity)			ACHE		D012721
CTD	decreases(activity)			ACHE		D012721
CTD	decreases(activity)			ACHE		D012721
CTD	increases(reaction)			ACHE		D012721
CTD	affects(reaction)			AHR		D012721
CTD	increases(expression)			AHR		D012721
CTD	affects(binding)			AHR		D012721
CTD	increases(activity)			AHR		D012721
CTD	affects(binding)			AHR		D012721
CTD	decreases(reaction)			AHR		D012721
CTD	increases(activity)			AHR		D012721
CTD	affects(reaction)			CYP1A1		D012721
CTD	increases(expression)			CYP1A1		D012721
CTD	decreases(reaction)			CYP1A1		D012721
CTD	increases(activity)			CYP1A1		D012721
CTD	increases(expression)			CYP1A1		D012721
CTD	decreases(reaction)			CYP1A2		D012721
CTD	increases(chemical synthesis)			CYP1A2		D012721
CTD	increases(metabolic processing)			CYP1A2		D012721
CTD	decreases(activity)			CYP1A2		D012721
CTD	increases(activity)			CYP2B6		D012721
CTD	increases(expression)			CYP2B6		D012721
CTD	decreases(reaction)			CYP2E1		D012721
CTD	increases(hydroxylation)			CYP2E1		D012721
CTD	decreases(activity)			CYP2E1		D012721
CTD	increases(expression)			CYP3A4		D012721
CTD	increases(expression)			DDIT3		D012721
CTD	affects(binding)			ESR1		D012721
CTD	decreases(activity)			ESR1		D012721
CTD	decreases(reaction)			ESR1		D012721
CTD	increases(activity)			ESR1		D012721
CTD	affects(binding)			ESR2		D012721
CTD	decreases(activity)			ESR2		D012721
CTD	increases(expression)			FOS		D012721
CTD	decreases(reaction)			FSHB		D012721
CTD	increases(expression)			FSHB		D012721
CTD	increases(secretion)			FSHB		D012721
CTD	increases(expression)			HSPA5		D012721
CTD	increases(phosphorylation)			NEFH		D012721
CTD	increases(expression)			NR1I2		D012721
CTD	decreases(reaction)			PGR		D012721
CTD	increases(activity)			PGR		D012721
CTD	decreases(reaction)			STAR		D012721
CTD	increases(expression)			STAR		D012721
CTD	decreases(expression)			STAR		D012721
CTD	affects(binding)			THRB		D012721
CTD	decreases(activity)			THRB		D012721
CTD	increases(activity)			TPO		D012721
PubChem	Potency-Replicate_1	uM	5.308	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	16.154	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.306	AHR	-	GI(Protien) :
PubChem	Potency	uM	35.481	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	35.721	AHR	-	GI(Protien) :
PubChem	Potency	uM	39.811	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	44.559	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	53.984	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	29.849	AR	-	GI(Protien) :
PubChem	Potency	uM	35.481	GAA	-	GI(Protien) :
PubChem	None	uM		KLK5	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	15.355	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	17.229	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	33.492	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	14.125	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	35481.300	GAA	-	Target : CHEMBL2608
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	39810.700	HSD17B10	-	Target : CHEMBL4159

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