Tan Lab | DSigDB

Gene Set: D4 : CTD - Serotonin

Collection

D4 : CTD

Chemical Name

Serotonin ( From PubChem : SEROTONIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
176.215 g/mol	3	2	2.075	True

Structure

InChI

InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2

InChIKey

QZAYGJVTTNCVMB-UHFFFAOYSA-N

Links

Gene (45 / 153)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(abundance)			CAT		D012701
CTD	decreases(reaction)			CAT		D012701
CTD	increases(activity)			CFTR		D012701
CTD	increases(reaction)			CFTR		D012701
CTD	affects(expression)			CXCL8		D012701
CTD	affects(secretion)			CXCL8		D012701
CTD	affects(binding)			GAPDH		D012701
CTD	affects(cotreatment)			GAPDH		D012701
CTD	affects(metabolic processing)			GAPDH		D012701
CTD	increases(phosphorylation)			GSK3B		D012701
CTD	affects(abundance)			HTR1D		D012701
CTD	decreases(response to substance)			HTR2A		D012701
CTD	affects(response to substance)			HTR2A		D012701
CTD	affects(binding)			HTR2A		D012701
CTD	increases(activity)			HTR2A		D012701
CTD	affects(binding)			HTR3A		D012701
CTD	increases(activity)			HTR3A		D012701
CTD	increases(reaction)			HTR3A		D012701
CTD	decreases(reaction)			HTR3A		D012701
CTD	affects(binding)			HTR3B		D012701
CTD	increases(activity)			HTR3B		D012701
CTD	increases(reaction)			HTR3B		D012701
CTD	decreases(reaction)			HTR3B		D012701
CTD	affects(binding)			HTR7		D012701
CTD	increases(abundance)			HTR7		D012701
CTD	increases(activity)			HTR7		D012701
CTD	affects(secretion)			IL12B		D012701
CTD	affects(secretion)			IL1B		D012701
CTD	affects(expression)			IL6		D012701
CTD	affects(secretion)			IL6		D012701
CTD	affects(abundance)			ITGB3		D012701
CTD	increases(abundance)			MAOA		D012701
CTD	increases(metabolic processing)			MAOA		D012701
CTD	decreases(reaction)			MAOA		D012701
CTD	increases(degradation)			MAOA		D012701
CTD	affects(binding)			MPO		D012701
CTD	affects(cotreatment)			MPO		D012701
CTD	affects(metabolic processing)			MPO		D012701
CTD	increases(reaction)			MPO		D012701
CTD	affects(abundance)			PARP1		D012701
CTD	decreases(reaction)			SLC18A1		D012701
CTD	increases(uptake)			SLC18A1		D012701
CTD	affects(binding)			SLC18A2		D012701
CTD	affects(uptake)			SLC18A2		D012701
CTD	decreases(reaction)			SLC22A16		D012701
CTD	increases(uptake)			SLC22A16		D012701
CTD	increases(activity)			SLC6A2		D012701
CTD	increases(reaction)			SLC6A2		D012701
CTD	increases(activity)			SLC6A3		D012701
CTD	increases(reaction)			SLC6A3		D012701
CTD	increases(uptake)			SLC6A3		D012701
CTD	increases(reaction)			SLC6A4		D012701
CTD	increases(uptake)			SLC6A4		D012701
CTD	affects(binding)			SLC6A4		D012701
CTD	affects(abundance)			SLC6A4		D012701
CTD	decreases(response to substance)			SLC6A4		D012701
CTD	decreases(uptake)			SLC6A4		D012701
CTD	increases(activity)			SLC6A4		D012701
CTD	increases(reaction)			SLC6A4		D012701
CTD	increases(uptake)			SLC6A4		D012701
CTD	affects(secretion)			STXBP3		D012701
CTD	increases(sulfation)			SULT1A1		D012701
CTD	increases(sulfation)			SULT1A3		D012701
CTD	increases(activity)			TAAR1		D012701
CTD	increases(reaction)			TAAR1		D012701
CTD	affects(secretion)			TNF		D012701
CTD	affects(abundance)			TPH1		D012701
CTD	increases(abundance)			TPH1		D012701
CTD	affects(reaction)			TRPA1		D012701
CTD	increases(secretion)			TRPA1		D012701
CTD	decreases(reaction)			UGT1A6		D012701
CTD	increases(glucuronidation)			UGT1A6		D012701
CTD	affects(glucuronidation)			UGT1A6		D012701
CTD	increases(glucuronidation)			UGT1A6		D012701
CTD	increases(glucuronidation)			UGT1A6		D012701
CTD	affects(binding)			XDH		D012701
CTD	affects(cotreatment)			XDH		D012701
CTD	affects(metabolic processing)			XDH		D012701
CTD	increases(reaction)			XDH		D012701
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	21.192	EHMT2	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR4		GI(Protien) :
PubChem	None	uM		HTR5A		GI(Protien) :
PubChem	None	uM		HTR5A		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
PubChem	Potency	uM	11.220	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	31.623	TSHR	-	GI(Protien) :
ChEMBL	AC50	nM	7943.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1995.260	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	21192.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	11220.200	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	31622.800	TSHR	-	Target : CHEMBL1963

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