Tan Lab | DSigDB

Gene Set: D4 : CTD - cinnamic aldehyde

Collection

D4 : CTD

Chemical Name

cinnamic aldehyde ( From PubChem : CINNAMALDEHYDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
132.159 g/mol	0	1	1.8987	True

Structure

InChI

InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+

InChIKey

KJPRLNWUNMBNBZ-QPJJXVBHSA-N

Links

Gene (165 / 264)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCC3		C012843
CTD	increases(expression)			ABHD12B		C012843
CTD	increases(expression)			ADAM23		C012843
CTD	increases(expression)			ADK		C012843
CTD	increases(expression)			ADM		C012843
CTD	increases(expression)			AKR1C1		C012843
CTD	increases(activity)			AKR1C2		C012843
CTD	increases(phosphorylation)			AKT1		C012843
CTD	increases(expression)			ALS2		C012843
CTD	increases(expression)			AMPD3		C012843
CTD	increases(expression)			ARHGAP23		C012843
CTD	increases(expression)			ATF3		C012843
CTD	increases(expression)			ATP11A		C012843
CTD	increases(expression)			BAX		C012843
CTD	decreases(reaction)			BAX		C012843
CTD	increases(expression)			BAX		C012843
CTD	increases(expression)			BCAP29		C012843
CTD	decreases(expression)			BCL2		C012843
CTD	decreases(expression)			BCL2		C012843
CTD	decreases(expression)			BCL2		C012843
CTD	decreases(reaction)			BCL2		C012843
CTD	increases(cleavage)			BID		C012843
CTD	decreases(expression)			BIRC2		C012843
CTD	decreases(reaction)			BIRC2		C012843
CTD	decreases(expression)			BIRC3		C012843
CTD	decreases(reaction)			BIRC3		C012843
CTD	increases(expression)			CASP1		C012843
CTD	increases(activity)			CASP3		C012843
CTD	increases(expression)			CASP3		C012843
CTD	increases(activity)			CASP3		C012843
CTD	increases(cleavage)			CASP3		C012843
CTD	decreases(reaction)			CASP3		C012843
CTD	increases(activity)			CASP8		C012843
CTD	increases(expression)			CCDC34		C012843
CTD	increases(secretion)			CCL5		C012843
CTD	increases(expression)			CD274		C012843
CTD	increases(expression)			CD86		C012843
CTD	increases(expression)			CD86		C012843
CTD	decreases(activity)			CDC25B		C012843
CTD	increases(expression)			CDKN1A		C012843
CTD	increases(expression)			CES1		C012843
CTD	decreases(expression)			CLK2		C012843
CTD	decreases(expression)			CNOT2		C012843
CTD	increases(expression)			COL7A1		C012843
CTD	decreases(expression)			CREB1		C012843
CTD	increases(expression)			CREM		C012843
CTD	increases(expression)			CRIM1		C012843
CTD	decreases(phosphorylation)			CRKL		C012843
CTD	decreases(expression)			CTGF		C012843
CTD	decreases(reaction)			CXCL8		C012843
CTD	increases(expression)			CXCL8		C012843
CTD	increases(expression)			CXCL8		C012843
CTD	increases(secretion)			CXCL8		C012843
CTD	affects(reaction)			CXCL8		C012843
CTD	increases(secretion)			CXCL8		C012843
CTD	affects(localization)			CYCS		C012843
CTD	decreases(reaction)			CYCS		C012843
CTD	increases(expression)			CYP7A1		C012843
CTD	increases(expression)			DDIT3		C012843
CTD	decreases(expression)			DDIT4		C012843
CTD	affects(localization)			DIABLO		C012843
CTD	decreases(reaction)			DIABLO		C012843
CTD	increases(expression)			DMTN		C012843
CTD	increases(expression)			DNAJB4		C012843
CTD	decreases(expression)			DNMT3B		C012843
CTD	decreases(expression)			DUSP6		C012843
CTD	increases(expression)			DYNLRB1		C012843
CTD	decreases(expression)			EAF2		C012843
CTD	increases(expression)			EGR1		C012843
CTD	increases(expression)			EPAS1		C012843
CTD	decreases(reaction)			F2RL1		C012843
CTD	increases(activity)			F2RL1		C012843
CTD	increases(reaction)			F2RL1		C012843
CTD	increases(expression)			FCGR2B		C012843
CTD	increases(expression)			FCGR2C		C012843
CTD	decreases(expression)			FGFR2		C012843
CTD	increases(expression)			FMO5		C012843
CTD	decreases(expression)			FOS		C012843
CTD	increases(expression)			FTH1		C012843
CTD	increases(expression)			FTL		C012843
CTD	increases(expression)			FZD2		C012843
CTD	increases(expression)			G6PD		C012843
CTD	decreases(reaction)			GCLC		C012843
CTD	increases(expression)			GCLC		C012843
CTD	increases(activity)			GCLC		C012843
CTD	increases(expression)			GCLC		C012843
CTD	increases(expression)			GCLC		C012843
CTD	affects(reaction)			GCLC		C012843
CTD	increases(activity)			GCLM		C012843
CTD	increases(expression)			GCLM		C012843
CTD	increases(expression)			GCLM		C012843
CTD	affects(activity)			GLRX		C012843
CTD	decreases(reaction)			GLRX		C012843
CTD	increases(glutathionylation)			GLRX		C012843
CTD	increases(activity)			GLRX		C012843
CTD	affects(localization)			GLRX		C012843
CTD	increases(expression)			GLRX		C012843
CTD	increases(expression)			GPR21		C012843
CTD	increases(expression)			GPX2		C012843
CTD	increases(expression)			GSR		C012843
CTD	affects(binding)			GSTP1		C012843
CTD	decreases(activity)			GSTP1		C012843
CTD	increases(expression)			HFE		C012843
CTD	decreases(reaction)			HMOX1		C012843
CTD	increases(expression)			HMOX1		C012843
CTD	increases(expression)			HMOX1		C012843
CTD	increases(expression)			HMOX1		C012843
CTD	increases(expression)			HMOX1		C012843
CTD	decreases(mutagenesis)			HPRT1		C012843
CTD	increases(expression)			HSPA1B		C012843
CTD	increases(expression)			HSPA6		C012843
CTD	increases(expression)			HSPH1		C012843
CTD	increases(expression)			HTATIP2		C012843
CTD	affects(localization)			HTRA2		C012843
CTD	decreases(reaction)			HTRA2		C012843
CTD	decreases(reaction)			ICAM1		C012843
CTD	increases(expression)			ICAM1		C012843
CTD	increases(activity)			ICAM1		C012843
CTD	decreases(expression)			IFI27		C012843
CTD	decreases(expression)			IFI44L		C012843
CTD	affects(cotreatment)			IL1B		C012843
CTD	decreases(reaction)			IL1B		C012843
CTD	increases(secretion)			IL1B		C012843
CTD	increases(expression)			IL1B		C012843
CTD	increases(expression)			IL7R		C012843
CTD	decreases(expression)			INSIG1		C012843
CTD	increases(expression)			ITGA11		C012843
CTD	decreases(expression)			JUN		C012843
CTD	decreases(expression)			JUND		C012843
CTD	increases(expression)			KEAP1		C012843
CTD	increases(expression)			LHFP		C012843
CTD	decreases(expression)			LMCD1		C012843
CTD	increases(expression)			LRP12		C012843
CTD	increases(expression)			LTA		C012843
CTD	increases(expression)			MAGIX		C012843
CTD	decreases(expression)			MAP2K2		C012843
CTD	increases(activity)			MAPK1		C012843
CTD	increases(phosphorylation)			MAPK1		C012843
CTD	decreases(reaction)			MAPK14		C012843
CTD	increases(phosphorylation)			MAPK14		C012843
CTD	increases(activity)			MAPK14		C012843
CTD	increases(activity)			MAPK3		C012843
CTD	increases(phosphorylation)			MAPK3		C012843
CTD	decreases(reaction)			MAPK8		C012843
CTD	increases(phosphorylation)			MAPK8		C012843
CTD	increases(activity)			MAPK8		C012843
CTD	increases(phosphorylation)			MAPK8		C012843
CTD	increases(expression)			MAPKAPK5		C012843
CTD	decreases(expression)			MARK4		C012843
CTD	decreases(expression)			MCL1		C012843
CTD	increases(expression)			MDM2		C012843
CTD	decreases(expression)			MX1		C012843
CTD	decreases(expression)			MYC		C012843
CTD	increases(expression)			MYC		C012843
CTD	increases(expression)			NBPF10		C012843
CTD	increases(expression)			NCF1		C012843
CTD	affects(localization)			NFE2L2		C012843
CTD	increases(expression)			NFE2L2		C012843
CTD	affects(localization)			NFE2L2		C012843
CTD	decreases(reaction)			NFE2L2		C012843
CTD	increases(activity)			NFE2L2		C012843
CTD	increases(expression)			NFE2L2		C012843
CTD	increases(glutathionylation)			NFE2L2		C012843
CTD	increases(expression)			NFE2L2		C012843
CTD	affects(reaction)			NFE2L2		C012843
CTD	increases(expression)			NFE2L2		C012843
CTD	decreases(expression)			NFKB1		C012843
CTD	increases(expression)			NINL		C012843
CTD	increases(expression)			NOTCH3		C012843
CTD	increases(expression)			NQO1		C012843
CTD	increases(activity)			NQO1		C012843
CTD	increases(expression)			NQO1		C012843
CTD	increases(expression)			PANX2		C012843
CTD	increases(cleavage)			PARP1		C012843
CTD	increases(expression)			PDE3B		C012843
CTD	increases(expression)			PHLDA2		C012843
CTD	increases(expression)			PIR		C012843
CTD	increases(expression)			PMAIP1		C012843
CTD	increases(expression)			POR		C012843
CTD	increases(expression)			PPFIBP1		C012843
CTD	decreases(expression)			PPP1R10		C012843
CTD	increases(expression)			PRDM5		C012843
CTD	affects(cotreatment)			PTGS2		C012843
CTD	decreases(reaction)			PTGS2		C012843
CTD	increases(expression)			PTGS2		C012843
CTD	affects(localization)			RELA		C012843
CTD	decreases(reaction)			RELA		C012843
CTD	decreases(abundance)			RELA		C012843
CTD	increases(glutathionylation)			RELA		C012843
CTD	affects(activity)			RELA		C012843
CTD	increases(abundance)			RELA		C012843
CTD	increases(activity)			RELA		C012843
CTD	decreases(expression)			RTN4RL1		C012843
CTD	increases(expression)			SEL1L3		C012843
CTD	increases(expression)			SERPINE1		C012843
CTD	increases(expression)			SGCD		C012843
CTD	increases(expression)			SLC14A1		C012843
CTD	increases(expression)			SLC1A2		C012843
CTD	increases(expression)			SLC26A7		C012843
CTD	increases(expression)			SLC2A13		C012843
CTD	decreases(expression)			SLC35D2		C012843
CTD	increases(expression)			SLC7A11		C012843
CTD	increases(expression)			SLC8A1		C012843
CTD	increases(expression)			SMAD2		C012843
CTD	increases(expression)			SNX24		C012843
CTD	increases(expression)			SQSTM1		C012843
CTD	increases(expression)			SRSF11		C012843
CTD	increases(expression)			SRXN1		C012843
CTD	increases(expression)			STAU2		C012843
CTD	decreases(expression)			STK24		C012843
CTD	increases(expression)			SUFU		C012843
CTD	decreases(expression)			SYNE2		C012843
CTD	affects(binding)			TBXA2R		C012843
CTD	decreases(activity)			TBXA2R		C012843
CTD	decreases(expression)			TGFB1I1		C012843
CTD	increases(expression)			THNSL2		C012843
CTD	increases(expression)			TLR4		C012843
CTD	affects(localization)			TNF		C012843
CTD	decreases(reaction)			TNF		C012843
CTD	increases(expression)			TNF		C012843
CTD	decreases(reaction)			TNF		C012843
CTD	increases(secretion)			TNF		C012843
CTD	affects(cotreatment)			TNF		C012843
CTD	decreases(reaction)			TNF		C012843
CTD	increases(secretion)			TNF		C012843
CTD	increases(activity)			TNF		C012843
CTD	increases(expression)			TNF		C012843
CTD	increases(expression)			TNFRSF21		C012843
CTD	decreases(expression)			TNNT2		C012843
CTD	decreases(expression)			TP53		C012843
CTD	increases(expression)			TRIM16		C012843
CTD	increases(expression)			TRIM16L		C012843
CTD	decreases(reaction)			TRPA1		C012843
CTD	increases(activity)			TRPA1		C012843
CTD	increases(activity)			TRPA1		C012843
CTD	increases(activity)			TRPA1		C012843
CTD	increases(transport)			TRPA1		C012843
CTD	decreases(reaction)			TRPA1		C012843
CTD	increases(activity)			TRPA1		C012843
CTD	increases(reaction)			TRPA1		C012843
CTD	affects(reaction)			TRPA1		C012843
CTD	increases(secretion)			TRPA1		C012843
CTD	increases(uptake)			TRPA1		C012843
CTD	affects(response to substance)			TRPA1		C012843
CTD	increases(response to substance)			TRPA1		C012843
CTD	decreases(expression)			TTN		C012843
CTD	increases(expression)			TXNRD1		C012843
CTD	increases(expression)			TXNRD1		C012843
CTD	increases(expression)			UBE2D1		C012843
CTD	increases(expression)			UGP2		C012843
CTD	decreases(expression)			UNG		C012843
CTD	decreases(expression)			XIAP		C012843
CTD	decreases(reaction)			XIAP		C012843
CTD	increases(expression)			ZDHHC21		C012843
CTD	increases(expression)			ZNF442		C012843
CTD	increases(expression)			ZNF506		C012843
CTD	increases(expression)			ZNF639		C012843
PubChem	Potency	uM	2.512	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	12.589	ALDH1A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.883	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	18.996	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	ESR1	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	2511.900	ALDH1A1	-	Target : CHEMBL3577

Download gene sets

gmt, text, Detailed text