Tan Lab | DSigDB

Gene Set: D4 : CTD - Riboflavin

Collection

D4 : CTD

Chemical Name

Riboflavin ( From PubChem : RIBOFLAVINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
376.364 g/mol	5	9	-1.6752	True

Structure

InChI

InChI=1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

InChIKey

AUNGANRZJHBGPY-SCRDCRAPSA-N

Links

Gene (33 / 60)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(expression)			ASPM		D012256
CTD	increases(expression)			BAX		D012256
CTD	decreases(expression)			BCL2		D012256
CTD	affects(expression)			BIRC5		D012256
CTD	affects(expression)			CCNB1		D012256
CTD	affects(cotreatment)			CRP		D012256
CTD	decreases(expression)			CRP		D012256
CTD	affects(cotreatment)			CXCL8		D012256
CTD	decreases(expression)			CXCL8		D012256
CTD	increases(reaction)			CXCL8		D012256
CTD	affects(expression)			DDIT3		D012256
CTD	affects(expression)			GSR		D012256
CTD	affects(cotreatment)			IL1B		D012256
CTD	decreases(expression)			IL1B		D012256
CTD	increases(reaction)			IL1B		D012256
CTD	affects(cotreatment)			IL6		D012256
CTD	decreases(expression)			IL6		D012256
CTD	increases(reaction)			IL6		D012256
CTD	affects(expression)			KIF23		D012256
CTD	affects(response to substance)			MTHFR		D012256
CTD	increases(expression)			MYC		D012256
CTD	affects(cotreatment)			PARP1		D012256
CTD	increases(expression)			PARP1		D012256
CTD	affects(expression)			PLAGL1		D012256
CTD	increases(expression)			PPARGC1A		D012256
CTD	affects(cotreatment)			TNF		D012256
CTD	decreases(expression)			TNF		D012256
CTD	increases(reaction)			TNF		D012256
CTD	increases(expression)			TP53		D012256
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	Potency	uM	31.623	USP1	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	6.310	EHMT2	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	Potency	uM	31.623	USP1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	45.073	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	45.073	AHR	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TRA	-	GI(Protien) :
PubChem	None	uM		TRA	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	BRCA1	-	Target : CHEMBL5990
ChEMBL	Potency	nM	112202.000	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	35481.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	3981.100	BRCA1	-	Target : CHEMBL5990
ChEMBL	AC50	nM	7943.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	6309.600	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	7943.300	BRCA1	-	Target : CHEMBL5990
ChEMBL	Potency	nM	15848.900	HSD17B10	-	Target : CHEMBL4159

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