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Gene Set: D4 : CTD - Ribavirin

Collection D4 : CTD
Chemical Name Ribavirin ( From PubChem : ICN 1229 )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
244.205 g/mol 4 9 -2.3112 True
Structure
InChI InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5+,8+/m1/s1
InChIKey IWUCXVSUMQZMFG-BWSHDJSZSA-N
Links

Gene (29 / 81)


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Source Type Unit Value Gene PMID Assay Other
CTDincreases(activity)CASP3
D012254
CTDincreases(reaction)CASP3
D012254
CTDincreases(activity)CASP7
D012254
CTDincreases(reaction)CASP7
D012254
CTDincreases(activity)CASP8
D012254
CTDincreases(reaction)CASP8
D012254
CTDaffects(cotreatment)EPO
D012254
CTDaffects(expression)EPO
D012254
CTDaffects(cotreatment)EPO
D012254
CTDincreases(expression)EPO
D012254
CTDincreases(expression)EPO
D012254
CTDincreases(activity)FAS
D012254
CTDincreases(reaction)FAS
D012254
CTDdecreases(expression)ICAM1
D012254
CTDaffects(cotreatment)IFNA2
D012254
CTDaffects(response to substance)IFNA2
D012254
CTDincreases(response to substance)IFNA2
D012254
CTDaffects(cotreatment)IFNA2
D012254
CTDaffects(reaction)IFNA2
D012254
CTDincreases(secretion)IFNA2
D012254
CTDaffects(binding)IFNA2
D012254
CTDincreases(reaction)IFNA2
D012254
CTDincreases(activity)IFNA2
D012254
CTDaffects(cotreatment)IFNG
D012254
CTDaffects(reaction)IFNG
D012254
CTDincreases(secretion)IFNG
D012254
CTDdecreases(reaction)IFNG
D012254
CTDdecreases(expression)IFNG
D012254
CTDincreases(expression)IFNG
D012254
CTDaffects(cotreatment)IFNL3
D012254
CTDaffects(response to substance)IFNL3
D012254
CTDaffects(cotreatment)IFNL3
D012254
CTDaffects(response to substance)IFNL3
D012254
CTDincreases(response to substance)IFNL3
D012254
CTDaffects(cotreatment)IL10
D012254
CTDaffects(reaction)IL10
D012254
CTDincreases(secretion)IL10
D012254
CTDdecreases(reaction)IL10
D012254
CTDdecreases(expression)IL10
D012254
CTDaffects(binding)IL12A
D012254
CTDaffects(cotreatment)IL12A
D012254
CTDincreases(reaction)IL12A
D012254
CTDincreases(secretion)IL12A
D012254
CTDaffects(binding)IL12B
D012254
CTDaffects(cotreatment)IL12B
D012254
CTDincreases(reaction)IL12B
D012254
CTDincreases(secretion)IL12B
D012254
CTDdecreases(reaction)IL1B
D012254
CTDincreases(secretion)IL1B
D012254
CTDaffects(cotreatment)IL2
D012254
CTDincreases(reaction)IL2
D012254
CTDincreases(secretion)IL2
D012254
CTDincreases(expression)IL2
D012254
CTDincreases(reaction)IL4
D012254
CTDincreases(secretion)IL4
D012254
CTDdecreases(expression)IL4
D012254
CTDdecreases(expression)IL5
D012254
CTDincreases(response to substance)ITPA
D012254
CTDaffects(cotreatment)OAS1
D012254
CTDincreases(activity)OAS1
D012254
CTDincreases(uptake)SLC29A1
D012254
CTDaffects(transport)SLC29A3
D012254
CTDincreases(reaction)SLC6A4
D012254
CTDincreases(uptake)SLC6A4
D012254
CTDincreases(activity)SLC6A4
D012254
CTDincreases(expression)SLC6A4
D012254
CTDdecreases(reaction)TNF
D012254
CTDincreases(secretion)TNF
D012254
CTDincreases(expression)TNF
D012254
CTDdecreases(response to substance)TNFSF10
D012254
CTDdecreases(expression)TXN
D012254
PubChem PotencyuM15.849SMN2-GI(Protien) :
PubChem PotencyuM25.119ALDH1A1-GI(Protien) :
PubChem PotencyuM66.824CXCL8-GI(Protien) :
PubChem Ratio Potency (uM)uM37.978ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM51.626ESR1-GI(Protien) :
PubChem PotencyuM1.032TDP1-GI(Protien) :
PubChem PotencyuM1.158TDP1-GI(Protien) :
PubChem PotencyuM1.158TDP1-GI(Protien) :
PubChem PotencyuM1.458TDP1-GI(Protien) :
ChEMBLPotencynM25118.900ALDH1A1
-Target : CHEMBL3577
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