Tan Lab | DSigDB

Gene Set: D4 : CTD - Retinaldehyde

Collection

D4 : CTD

Chemical Name

Retinaldehyde ( From PubChem : RETINAL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
284.436 g/mol	0	1	5.7169	False(3/4)

Structure

InChI

InChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

InChIKey

NCYCYZXNIZJOKI-OVSJKPMPSA-N

Links

Gene (28 / 43)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(metabolic processing)			ADH1B		D012172
CTD	increases(reduction)			AKR1B1		D012172
CTD	increases(metabolic processing)			AKR1B10		D012172
CTD	increases(reduction)			AKR1B10		D012172
CTD	increases(reduction)			AKR1C3		D012172
CTD	affects(binding)			ALB		D012172
CTD	affects(binding)			ALDH1A1		D012172
CTD	affects(metabolic processing)			ALDH1A1		D012172
CTD	affects(binding)			ALDH1A1		D012172
CTD	increases(oxidation)			ALDH1A1		D012172
CTD	affects(cotreatment)			ALDH1A1		D012172
CTD	increases(oxidation)			ALDH1A1		D012172
CTD	increases(oxidation)			ALDH1A3		D012172
CTD	affects(cotreatment)			ALDH2		D012172
CTD	increases(oxidation)			ALDH2		D012172
CTD	increases(metabolic processing)			ALDH2		D012172
CTD	increases(expression)			AREG		D012172
CTD	decreases(expression)			BTC		D012172
CTD	affects(cotreatment)			CYP26A1		D012172
CTD	increases(expression)			CYP26A1		D012172
CTD	increases(expression)			HBEGF		D012172
CTD	increases(expression)			PPARGC1A		D012172
CTD	affects(binding)			RBP1		D012172
CTD	affects(metabolic processing)			RBP1		D012172
CTD	increases(metabolic processing)			RDH12		D012172
CTD	increases(chemical synthesis)			RPE65		D012172
CTD	increases(reduction)			SDR16C5		D012172
PubChem	Potency	uM	22.387	ALDH1A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.234	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	60.758	AR	-	GI(Protien) :
PubChem	Potency	uM	0.422	CXCL8	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.262	CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	12.228	ESR1	-	GI(Protien) :
PubChem	Potency	uM	44.668	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.703	ESR1	-	GI(Protien) :
PubChem	None	uM		MAPT	-	GI(Protien) :
PubChem	Potency	uM	29.849	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.313	NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.080	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.703	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		PPARG	-	GI(Protien) :
ChEMBL	Potency	nM	22387.200	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Activity	-		OPN1LW	-	Target : CHEMBL1949482

Download gene sets

gmt, text, Detailed text