Tan Lab | DSigDB

Gene Set: D4 : CTD - Quinacrine

Collection

D4 : CTD

Chemical Name

Quinacrine ( From PubChem : QUINACRINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
399.957 g/mol	1	4	6.0454	False(3/4)

Structure

InChI

InChI=1S/C23H30ClN3O/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26)/t16-/m0/s1

InChIKey

GPKJTRJOBQGKQK-INIZCTEOSA-N

Links

Gene (15 / 30)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(response to substance)			BAX		D011796
CTD	increases(activity)			TP53		D011796
CTD	increases(activity)			TP53		D011796
CTD	increases(stability)			TP53		D011796
PubChem	Potency	uM	2.592	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	11.220	DRD1	-	GI(Protien) :
PubChem	Potency	uM	8.437	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	10.621	FEN1	-	GI(Protien) :
PubChem	Potency	uM	12.589	FEN1	-	GI(Protien) :
PubChem	Potency	uM	15.003	FEN1	-	GI(Protien) :
PubChem	Potency	uM	14.689	MTOR	-	GI(Protien) :
PubChem	Potency	uM	16.482	MTOR	-	GI(Protien) :
PubChem	Potency	uM	18.493	MTOR	-	GI(Protien) :
PubChem	Potency	uM	19.953	POLI	-	GI(Protien) :
PubChem	Potency	uM	50.119	POLK	-	GI(Protien) :
PubChem	Potency	uM	21.192	RGS4	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	4.467	TDP1	-	GI(Protien) :
PubChem	Potency	uM	5.623	TDP1	-	GI(Protien) :
PubChem	Potency	uM	20.970	USP1	-	GI(Protien) :
PubChem	Potency	uM	79.433	USP1	-	GI(Protien) :
ChEMBL	Potency	nM	2591.800	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	11220.200	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	8436.800	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	15003.000	FEN1	-	Target : CHEMBL5027
ChEMBL	Potency	nM	16481.600	MTOR	-	Target : CHEMBL2842
ChEMBL	Potency	nM	18492.700	MTOR	-	Target : CHEMBL2842
ChEMBL	Potency	nM	14689.200	MTOR	-	Target : CHEMBL2842
ChEMBL	Potency	nM	10000.000	NPSR1	-	Target : CHEMBL5162
ChEMBL	Potency	nM	7079.500	POLB	-	Target : CHEMBL2392

Download gene sets

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