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Gene Set: D4 : CTD - Pyrogallol

Collection D4 : CTD
Chemical Name Pyrogallol ( From PubChem : PYROGALLOL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotApprovedNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
126.11 g/mol 3 3 0.8034 True
Structure
InChI InChI=1S/C6H6O3/c7-4-2-1-3-5(8)6(4)9/h1-3,7-9H
InChIKey WQGWDDDVZFFDIG-UHFFFAOYSA-N
Links

Gene (30 / 54)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(binding)APP
D011748
CTDincreases(oxidation)APP
D011748
CTDincreases(reaction)APP
D011748
CTDdecreases(reaction)CASP3
D011748
CTDincreases(activity)CASP3
D011748
CTDdecreases(reaction)CASP3
D011748
CTDincreases(activity)CASP3
D011748
CTDincreases(activity)CASP3
D011748
CTDincreases(activity)CASP8
D011748
CTDdecreases(expression)CAT
D011748
CTDincreases(reaction)CAT
D011748
CTDincreases(methylation)COMT
D011748
CTDaffects(localization)CYCS
D011748
CTDaffects(binding)SNCA
D011748
CTDdecreases(reaction)SNCA
D011748
CTDdecreases(reaction)TP53
D011748
CTDincreases(expression)TP53
D011748
PubChem AhR Potency (uM)uM42.881AHR-GI(Protien) :
PubChem PotencyuM1.499ALDH1A1-GI(Protien) :
PubChem PotencyuM12.589ALOX15-GI(Protien) :
PubChem NoneuMAPOBEC3A-GI(Protien) :
PubChem NoneuMAPOBEC3A-GI(Protien) :
PubChem PotencyuM0.888CBFB-GI(Protien) :
PubChem PotencyuM3.965CBFB-GI(Protien) :
PubChem PotencyuM74.978CXCL8-GI(Protien) :
PubChem PotencyuM3.548EHMT2-GI(Protien) :
PubChem Potency-Replicate_1uM5.956ESR1-GI(Protien) :
PubChem PotencyuM8.912ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM21.314ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM24.826ESR1-GI(Protien) :
PubChem Ratio Potency (uM)uM45.837ESR1-GI(Protien) :
PubChem Potency-Replicate_1uM54.471ESR1-GI(Protien) :
PubChem NoneuMGFER-GI(Protien) :
PubChem NoneuMGSTO1-GI(Protien) :
PubChem PotencyuM10.000HPGD-GI(Protien) :
PubChem NoneuMMCL1-GI(Protien) :
PubChem NoneuMMCL1-GI(Protien) :
PubChem PotencyuM5.956NFE2L2-GI(Protien) :
PubChem NoneuMPLA2G7-GI(Protien) :
PubChem PotencyuM2.994POLK-GI(Protien) :
PubChem PotencyuM0.888RUNX1-GI(Protien) :
PubChem PotencyuM3.965RUNX1-GI(Protien) :
PubChem PotencyuM5.957TDP1-GI(Protien) :
PubChem PotencyuM79.433VDR-GI(Protien) :
ChEMBLActivity-ALB
-Target : CHEMBL3253
ChEMBLPotencynM1498.900ALDH1A1
-Target : CHEMBL3577
ChEMBLPotencynM12589.300ALOX15
-Target : CHEMBL2903
ChEMBLPotencynM1258.900APEX1
-Target : CHEMBL5619
ChEMBLPotencynM3965.000CBFB
-Target : CHEMBL2093862
ChEMBLPotencynM3548.100EHMT2
-Target : CHEMBL6032
ChEMBLPotencynM10000.000HPGD
-Target : CHEMBL1293255
ChEMBLPotencynM631.000HSD17B10
-Target : CHEMBL4159
ChEMBLPotencynM6309.600RECQL
-Target : CHEMBL1293236
ChEMBLPotencynM3965.000RUNX1
-Target : CHEMBL2093862
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