Tan Lab | DSigDB

Gene Set: D4 : CTD - Propylthiouracil

Collection

D4 : CTD

Chemical Name

Propylthiouracil ( From PubChem : PROPYLTHIOURACIL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Not	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
170.232 g/mol	2	2	1.385	True

Structure

InChI

InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

InChIKey

Links

Gene (21 / 22)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(response to substance)			CA6		D011441
CTD	decreases(expression)			CCL2		D011441
CTD	decreases(expression)			CTSB		D011441
CTD	decreases(activity)			DIO1		D011441
CTD	increases(expression)			ID2		D011441
CTD	increases(expression)			ID3		D011441
CTD	decreases(expression)			ITGB5		D011441
CTD	increases(expression)			KLF9		D011441
CTD	decreases(expression)			LRP2		D011441
CTD	decreases(activity)			MPO		D011441
CTD	affects(response to substance)			PRB1		D011441
CTD	affects(response to substance)			TAS2R38		D011441
CTD	increases(expression)			TBX3		D011441
CTD	decreases(expression)			TG		D011441
CTD	decreases(activity)			TPO		D011441
CTD	decreases(expression)			TPO		D011441
CTD	increases(expression)			ZNF676		D011441
PubChem	Potency-Replicate_1	uM	26.603	ESR1	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289

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