Tan Lab | DSigDB

Gene Set: D4 : CTD - Piribedil

Collection

D4 : CTD

Chemical Name

Piribedil ( From PubChem : PIRIBEDIL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
298.34 g/mol	0	6	1.5304	True

Structure

InChI

InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2

InChIKey

Links

Gene (8 / 34)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			DRD2		D010891
CTD	increases(activity)			DRD2		D010891
CTD	affects(binding)			DRD3		D010891
CTD	increases(activity)			DRD3		D010891
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.631	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	1.995	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	0.200	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	1.000	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	3.162	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
ChEMBL	AC50	nM	3162.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	6309.570	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1995.260	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	631.000	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	1995.260	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	630.960	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	1995.300	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	199.530	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	1000.000	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	1000.000	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	199.500	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	3162.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	3162.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	CYP3A4	-	Target : CHEMBL340

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