Tan Lab | DSigDB

Gene Set: D4 : CTD - Pirenzepine

Collection

D4 : CTD

Chemical Name

Pirenzepine ( From PubChem : PIRENZEPINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
351.402 g/mol	1	6	1.2034	True

Structure

InChI

InChI=1S/C19H21N5O2/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24/h2-8H,9-13H2,1H3,(H,21,26)

InChIKey

Links

Gene (6 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			CD40		D010890
CTD	increases(expression)			CD40		D010890
CTD	affects(binding)			CHRM1		D010890
CTD	affects(reaction)			CHRM1		D010890
CTD	affects(binding)			CHRM1		D010890
CTD	decreases(reaction)			CHRM1		D010890
CTD	affects(binding)			CHRM1		D010890
CTD	decreases(reaction)			CHRM1		D010890
CTD	affects(binding)			CHRM5		D010890
CTD	decreases(reaction)			CHRM5		D010890
PubChem	Potency	uM	31.623	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	3.663	DRD1	-	GI(Protien) :
PubChem	Potency	uM	29.935	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	56.234	EHMT2	-	GI(Protien) :
ChEMBL	AC50	nM	31622.800	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	31622.800	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	29934.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	56234.100	EHMT2	-	Target : CHEMBL6032

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