Tan Lab | DSigDB

Gene Set: D4 : CTD - Phenylephrine

Collection

D4 : CTD

Chemical Name

Phenylephrine ( From PubChem : PHENYLEPHRINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
167.205 g/mol	3	3	1.0359	True

Structure

InChI

InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1

InChIKey

SONNWYBIRXJNDC-VIFPVBQESA-N

Links

Gene (33 / 118)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(response to substance)			ACE		D010656
CTD	decreases(response to substance)			ADM		D010656
CTD	decreases(reaction)			ADRA1A		D010656
CTD	increases(abundance)			ADRA1A		D010656
CTD	increases(activity)			ADRA1A		D010656
CTD	affects(response to substance)			ADRA1A		D010656
CTD	affects(cotreatment)			ADRA1A		D010656
CTD	decreases(reaction)			ADRA1A		D010656
CTD	increases(phosphorylation)			ADRA1A		D010656
CTD	increases(abundance)			ADRA1A		D010656
CTD	increases(activity)			ADRA1A		D010656
CTD	affects(binding)			ADRA1A		D010656
CTD	affects(cotreatment)			ADRA1A		D010656
CTD	affects(reaction)			ADRA1A		D010656
CTD	affects(transport)			ADRA1A		D010656
CTD	increases(activity)			ADRA1A		D010656
CTD	affects(cotreatment)			ADRA1A		D010656
CTD	affects(response to substance)			ADRA1A		D010656
CTD	decreases(reaction)			ADRA1A		D010656
CTD	decreases(transport)			ADRA1A		D010656
CTD	increases(activity)			ADRA1A		D010656
CTD	affects(binding)			ADRA1A		D010656
CTD	affects(abundance)			ADRA1A		D010656
CTD	decreases(activity)			ADRA1A		D010656
CTD	increases(activity)			ADRA1A		D010656
CTD	affects(transport)			ADRA1A		D010656
CTD	increases(abundance)			ADRA1A		D010656
CTD	increases(activity)			ADRA1A		D010656
CTD	affects(response to substance)			ADRA1B		D010656
CTD	affects(cotreatment)			ADRA1B		D010656
CTD	decreases(reaction)			ADRA1B		D010656
CTD	increases(phosphorylation)			ADRA1B		D010656
CTD	increases(abundance)			ADRA1B		D010656
CTD	increases(activity)			ADRA1B		D010656
CTD	increases(activity)			ADRA1B		D010656
CTD	increases(abundance)			ADRA1B		D010656
CTD	affects(response to substance)			ADRA1D		D010656
CTD	affects(cotreatment)			ADRA1D		D010656
CTD	decreases(reaction)			ADRA1D		D010656
CTD	increases(phosphorylation)			ADRA1D		D010656
CTD	increases(abundance)			ADRA1D		D010656
CTD	increases(activity)			ADRA1D		D010656
CTD	affects(binding)			ADRA1D		D010656
CTD	affects(binding)			ADRA2A		D010656
CTD	increases(activity)			ADRA2A		D010656
CTD	increases(reaction)			ADRA2A		D010656
CTD	decreases(reaction)			ADRA2A		D010656
CTD	increases(response to substance)			ADRB3		D010656
CTD	decreases(reaction)			ADRB3		D010656
CTD	increases(abundance)			AGT		D010656
CTD	increases(reaction)			AGT		D010656
CTD	increases(response to substance)			AGT		D010656
CTD	decreases(reaction)			AGT		D010656
CTD	increases(response to substance)			ATP2B4		D010656
CTD	decreases(reaction)			CAV3		D010656
CTD	increases(expression)			CAV3		D010656
CTD	increases(phosphorylation)			CAV3		D010656
CTD	decreases(response to substance)			CAV3		D010656
CTD	increases(expression)			CDKN1A		D010656
CTD	increases(stability)			CDKN1A		D010656
CTD	increases(activity)			EDN1		D010656
CTD	increases(expression)			EDN1		D010656
CTD	increases(reaction)			EDN1		D010656
CTD	increases(activity)			EP300		D010656
CTD	increases(expression)			EP300		D010656
CTD	increases(reaction)			EP300		D010656
CTD	increases(expression)			FN1		D010656
CTD	increases(activity)			GATA4		D010656
CTD	increases(expression)			GATA4		D010656
CTD	increases(reaction)			GATA4		D010656
CTD	affects(expression)			GDF15		D010656
CTD	decreases(activity)			KCND3		D010656
CTD	decreases(reaction)			KCND3		D010656
CTD	affects(cotreatment)			KCND3		D010656
CTD	affects(response to substance)			KCND3		D010656
CTD	affects(reaction)			KCNH2		D010656
CTD	increases(transport)			KCNH2		D010656
CTD	affects(response to substance)			LPL		D010656
CTD	affects(cotreatment)			MAPK1		D010656
CTD	decreases(reaction)			MAPK1		D010656
CTD	increases(phosphorylation)			MAPK1		D010656
CTD	decreases(reaction)			MAPK1		D010656
CTD	increases(phosphorylation)			MAPK1		D010656
CTD	increases(activity)			MAPK1		D010656
CTD	increases(phosphorylation)			MAPK1		D010656
CTD	affects(cotreatment)			MAPK1		D010656
CTD	affects(reaction)			MAPK1		D010656
CTD	affects(cotreatment)			MAPK3		D010656
CTD	decreases(reaction)			MAPK3		D010656
CTD	increases(phosphorylation)			MAPK3		D010656
CTD	decreases(reaction)			MAPK3		D010656
CTD	increases(phosphorylation)			MAPK3		D010656
CTD	increases(activity)			MAPK3		D010656
CTD	increases(phosphorylation)			MAPK3		D010656
CTD	affects(cotreatment)			MAPK3		D010656
CTD	affects(reaction)			MAPK3		D010656
CTD	increases(expression)			MMP9		D010656
CTD	affects(cotreatment)			MYBPC3		D010656
CTD	increases(response to substance)			MYBPC3		D010656
CTD	decreases(reaction)			MYH7		D010656
CTD	increases(expression)			MYH7		D010656
CTD	decreases(reaction)			MYL7		D010656
CTD	increases(phosphorylation)			MYL7		D010656
CTD	decreases(reaction)			NFATC4		D010656
CTD	increases(localization)			NFATC4		D010656
CTD	increases(secretion)			NPPA		D010656
CTD	increases(response to substance)			POMC		D010656
CTD	decreases(activity)			REN		D010656
CTD	affects(cotreatment)			RGS3		D010656
CTD	affects(reaction)			RGS3		D010656
CTD	increases(activity)			RGS3		D010656
CTD	increases(phosphorylation)			RGS3		D010656
CTD	affects(cotreatment)			RGS4		D010656
CTD	affects(reaction)			RGS4		D010656
CTD	increases(activity)			RGS4		D010656
CTD	increases(phosphorylation)			RGS4		D010656
CTD	increases(expression)			TGFB1		D010656
PubChem	Potency	uM	1.836	DRD1	-	GI(Protien) :

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