Tan Lab | DSigDB

Gene Set: D4 : CTD - Penicillamine

Collection

D4 : CTD

Chemical Name

Penicillamine ( From PubChem : D-PENICILLAMINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
149.211 g/mol	3	4	0.807	True

Structure

InChI

InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1

InChIKey

VVNCNSJFMMFHPL-VKHMYHEASA-N

Links

Gene (49 / 80)

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Source	Type	Gene	Other
CTD	affects(binding)	APP	D010396
CTD	affects(cotreatment)	APP	D010396
CTD	decreases(reaction)	APP	D010396
CTD	increases(chemical synthesis)	APP	D010396
CTD	increases(oxidation)	APP	D010396
CTD	decreases(reaction)	APP	D010396
CTD	increases(activity)	APP	D010396
CTD	increases(metabolic processing)	APP	D010396
CTD	increases(activity)	ATF6	D010396
CTD	increases(metabolic processing)	ATF6	D010396
CTD	affects(binding)	ATP7A	D010396
CTD	affects(cotreatment)	ATP7A	D010396
CTD	increases(reaction)	ATP7A	D010396
CTD	affects(binding)	ATP7B	D010396
CTD	affects(cotreatment)	ATP7B	D010396
CTD	increases(reaction)	ATP7B	D010396
CTD	decreases(expression)	BBC3	D010396
CTD	decreases(expression)	BCL2	D010396
CTD	affects(binding)	C1S	D010396
CTD	decreases(reaction)	C1S	D010396
CTD	affects(binding)	C4A	D010396
CTD	decreases(reaction)	C4A	D010396
CTD	affects(binding)	C4B	D010396
CTD	decreases(reaction)	C4B	D010396
CTD	decreases(reaction)	CASP3	D010396
CTD	increases(activity)	CASP3	D010396
CTD	increases(cleavage)	CASP3	D010396
CTD	decreases(expression)	CAT	D010396
CTD	increases(expression)	CCL3	D010396
CTD	increases(expression)	CCL4	D010396
CTD	affects(binding)	CLU	D010396
CTD	affects(cotreatment)	CLU	D010396
CTD	increases(reaction)	CLU	D010396
CTD	decreases(expression)	CRP	D010396
CTD	increases(expression)	CYP1A1	D010396
CTD	increases(expression)	CYP2E1	D010396
CTD	increases(expression)	DDIT3	D010396
CTD	increases(expression)	DDIT3	D010396
CTD	increases(expression)	EGR1	D010396
CTD	increases(activity)	EIF2AK3	D010396
CTD	increases(phosphorylation)	EIF2AK3	D010396
CTD	increases(phosphorylation)	EIF2S1	D010396
CTD	affects(localization)	ELN	D010396
CTD	increases(expression)	FMO1	D010396
CTD	increases(expression)	FMO5	D010396
CTD	increases(expression)	GADD45A	D010396
CTD	increases(expression)	GSTM3	D010396
CTD	affects(response to substance)	HLA-A	D010396
CTD	affects(response to substance)	HLA-B	D010396
CTD	increases(response to substance)	HLA-DRB1	D010396
CTD	decreases(expression)	HMOX1	D010396
CTD	affects(cotreatment)	HMOX1	D010396
CTD	increases(expression)	HMOX1	D010396
CTD	increases(expression)	HMOX1	D010396
CTD	decreases(expression)	HP	D010396
CTD	increases(expression)	HSPA1A	D010396
CTD	increases(expression)	HSPA1L	D010396
CTD	increases(expression)	HSPA2	D010396
CTD	increases(expression)	HSPA5	D010396
CTD	increases(expression)	HSPA6	D010396
CTD	decreases(reaction)	IGF1	D010396
CTD	increases(activity)	IGF1	D010396
CTD	decreases(activity)	LOXL2	D010396
CTD	decreases(expression)	MCL1	D010396
CTD	decreases(reaction)	MCL1	D010396
CTD	decreases(secretion)	MPO	D010396
CTD	decreases(reaction)	MTR	D010396
CTD	increases(activity)	MTR	D010396
CTD	increases(expression)	NOS2	D010396
CTD	increases(cleavage)	PARP1	D010396
CTD	increases(expression)	PMAIP1	D010396
CTD	decreases(expression)	PMAIP1	D010396
CTD	decreases(reaction)	PMAIP1	D010396
CTD	decreases(reaction)	PRL	D010396
CTD	increases(expression)	PRL	D010396
CTD	increases(expression)	PTGS1	D010396
CTD	decreases(activity)	SOD1	D010396
CTD	decreases(expression)	TP53	D010396
CTD	increases(expression)	TP53	D010396
CTD	increases(splicing)	XBP1	D010396

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