Tan Lab | DSigDB

Gene Set: D4 : CTD - Patulin

Collection

D4 : CTD

Chemical Name

Patulin ( From PubChem : PATULIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
154.12 g/mol	1	4	-0.2979	True

Structure

InChI

InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2/t7-/m0/s1

InChIKey

ZRWPUFFVAOMMNM-ZETCQYMHSA-N

Links

Gene (31 / 56)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ATF3		D010365
CTD	increases(expression)			BCL2L11		D010365
CTD	increases(expression)			BID		D010365
CTD	decreases(response to substance)			CAT		D010365
CTD	affects(localization)			CLDN1		D010365
CTD	affects(localization)			CLDN3		D010365
CTD	affects(localization)			CLDN4		D010365
CTD	decreases(reaction)			CXCL8		D010365
CTD	increases(expression)			CXCL8		D010365
CTD	increases(expression)			DDIT3		D010365
CTD	decreases(abundance)			IFNG		D010365
CTD	decreases(secretion)			IFNG		D010365
CTD	decreases(expression)			IFNG		D010365
CTD	decreases(secretion)			IFNG		D010365
CTD	decreases(abundance)			IL10		D010365
CTD	decreases(secretion)			IL10		D010365
CTD	decreases(abundance)			IL13		D010365
CTD	decreases(secretion)			IL13		D010365
CTD	decreases(reaction)			IL1B		D010365
CTD	increases(expression)			IL1B		D010365
CTD	affects(secretion)			IL4		D010365
CTD	decreases(abundance)			IL4		D010365
CTD	decreases(secretion)			IL4		D010365
CTD	increases(expression)			IL4		D010365
CTD	decreases(reaction)			MAPK1		D010365
CTD	increases(phosphorylation)			MAPK1		D010365
CTD	decreases(reaction)			MAPK3		D010365
CTD	increases(phosphorylation)			MAPK3		D010365
CTD	decreases(reaction)			OCLN		D010365
CTD	increases(degradation)			OCLN		D010365
CTD	increases(expression)			PMAIP1		D010365
CTD	increases(expression)			PPP1R15A		D010365
CTD	decreases(response to substance)			SOD1		D010365
CTD	decreases(expression)			TJP1		D010365
CTD	increases(expression)			TP53		D010365
CTD	increases(splicing)			XBP1		D010365
PubChem	Potency	uM	31.623	MAPK1	-	GI(Protien) :
PubChem	Potency	uM	1.995	MAPT	-	GI(Protien) :
PubChem	Potency	uM	2.239	MAPT	-	GI(Protien) :
PubChem	Potency	uM	19.953	PPARG	-	GI(Protien) :
PubChem	Potency	uM	0.103	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.146	TDP1	-	GI(Protien) :
PubChem	Potency	uM	7.943	TP53	-	GI(Protien) :
PubChem	Potency	uM	12.589	TP53	-	GI(Protien) :
PubChem	Potency	uM	50.119	USP1	-	GI(Protien) :
PubChem	Potency	uM	12.589	VDR	-	GI(Protien) :
ChEMBL	Activity	-		CDK1	-	Target : CHEMBL308
ChEMBL	Activity	-		CDK1	-	Target : CHEMBL308
ChEMBL	Activity	-		CFL1	-	Target : CHEMBL1075129
ChEMBL	Activity	-		JUN	-	Target : CHEMBL4977
ChEMBL	Potency	nM	31622.800	MAPK1	-	Target : CHEMBL4040
ChEMBL	Potency	nM	1995.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	2238.700	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	12589.300	TP53	-	Target : CHEMBL4096
ChEMBL	Potency	nM	7943.300	TP53	-	Target : CHEMBL4096
ChEMBL	Activity	-		TP53	-	Target : CHEMBL4096

Download gene sets

gmt, text, Detailed text