Tan Lab | DSigDB

Gene Set: D4 : CTD - Norfloxacin

Collection

D4 : CTD

Chemical Name

Norfloxacin ( From PubChem : NORFLOXACIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
319.331 g/mol	2	6	1.6621	True

Structure

InChI

InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

InChIKey

Links

Gene (10 / 22)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			IL1B		D009643
CTD	increases(expression)			IL1B		D009643
CTD	increases(secretion)			IL1B		D009643
CTD	increases(reaction)			IL1B		D009643
CTD	increases(expression)			MMP1		D009643
CTD	increases(reaction)			MMP1		D009643
CTD	increases(secretion)			MMP1		D009643
CTD	decreases(reaction)			MMP13		D009643
CTD	increases(expression)			MMP13		D009643
CTD	increases(secretion)			MMP13		D009643
CTD	decreases(expression)			MMP13		D009643
CTD	decreases(reaction)			SLC22A2		D009643
CTD	increases(uptake)			SLC22A2		D009643
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	Potency	uM	8.912	EHMT2	-	GI(Protien) :
PubChem	None	uM		MAP3K3	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
ChEMBL	Potency	nM	8912.500	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	15848.900	KDM4E	-	Target : CHEMBL1293226

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