Tan Lab | DSigDB

Gene Set: D4 : CTD - Norethindrone

Collection

D4 : CTD

Chemical Name

Norethindrone ( From PubChem : NORETHINDRONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
298.419 g/mol	1	2	3.4925	True

Structure

InChI

InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1

InChIKey

VIKNJXKGJWUCNN-XGXHKTLJSA-N

Links

Gene (25 / 56)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCB1		D009640
CTD	decreases(activity)			ABCB11		D009640
CTD	decreases(activity)			AKR1C1		D009640
CTD	decreases(activity)			AKR1C3		D009640
CTD	increases(secretion)			BGLAP		D009640
CTD	affects(binding)			F10		D009640
CTD	increases(expression)			F10		D009640
CTD	affects(binding)			F7		D009640
CTD	increases(expression)			F7		D009640
CTD	increases(activity)			FASN		D009640
CTD	affects(binding)			FGA		D009640
CTD	affects(cotreatment)			FGA		D009640
CTD	increases(expression)			FGA		D009640
CTD	affects(binding)			FGB		D009640
CTD	affects(cotreatment)			FGB		D009640
CTD	increases(expression)			FGB		D009640
CTD	affects(binding)			FGG		D009640
CTD	affects(cotreatment)			FGG		D009640
CTD	increases(expression)			FGG		D009640
CTD	increases(phosphorylation)			H2AFX		D009640
CTD	decreases(expression)			MAPT		D009640
CTD	affects(binding)			PGR		D009640
CTD	increases(activity)			PGR		D009640
CTD	affects(binding)			PLG		D009640
CTD	increases(expression)			PLG		D009640
CTD	affects(binding)			PROC		D009640
CTD	increases(expression)			PROC		D009640
CTD	affects(binding)			SERPINC1		D009640
CTD	decreases(expression)			SERPINC1		D009640
CTD	affects(binding)			SERPINE1		D009640
CTD	decreases(expression)			SERPINE1		D009640
CTD	decreases(reaction)			SLC22A2		D009640
CTD	increases(uptake)			SLC22A2		D009640
CTD	increases(activity)			TP53		D009640
CTD	increases(expression)			TP53		D009640
CTD	increases(expression)			VEGFA		D009640
PubChem	Potency-Replicate_1	uM	0.002	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.002	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.009	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.009	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.031	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.034	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.038	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.054	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.094	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.022	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.110	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.237	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.397	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.345	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.396	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.337	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	25.289	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.977	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.378	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :

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