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Gene Set: D4 : CTD - Nitrazepam

Collection D4 : CTD
Chemical Name Nitrazepam ( From PubChem : NITRAZEPAM )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotApprovedNotNotNot4
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
281.266 g/mol 1 3 2.4811 True
Structure
InChI InChI=1S/C15H11N3O3/c19-14-9-16-15(10-4-2-1-3-5-10)12-8-11(18(20)21)6-7-13(12)17-14/h1-8H,9H2,(H,17,19)
InChIKey KJONHKAYOJNZEC-UHFFFAOYSA-N
Links

Gene (9 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(activity)AKR1C1
D009567
CTDdecreases(activity)AKR1C2
D009567
CTDdecreases(activity)AKR1C3
D009567
CTDdecreases(activity)AKR1C4
D009567
CTDaffects(reaction)CASP3
D009567
CTDincreases(activity)CASP3
D009567
CTDaffects(reaction)CASP7
D009567
CTDincreases(activity)CASP7
D009567
CTDaffects(reaction)CYP3A4
D009567
CTDincreases(activity)CYP3A4
D009567
CTDincreases(metabolic processing)CYP3A4
D009567
PubChem PotencyuM25.119HPGD-GI(Protien) :
PubChem NoneuMIL1B-GI(Protien) :
ChEMBLPotencynM25118.900HPGD
-Target : CHEMBL1293255
Download gene sets gmt, text, Detailed text
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