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Gene Set: D4 : CTD - Naltrexone

Collection D4 : CTD
Chemical Name Naltrexone ( From PubChem : NALTREXONE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
341.401 g/mol 2 5 1.4633 True
Structure
InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1
InChIKey DQCKKXVULJGBQN-XFWGSAIBSA-N
Links

Gene (8 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(response to substance)DRD2
D009271
CTDincreases(expression)FSHB
D009271
CTDincreases(secretion)FSHB
D009271
CTDaffects(response to substance)GABRA6
D009271
CTDaffects(response to substance)GABRB2
D009271
CTDincreases(expression)LHB
D009271
CTDincreases(secretion)LHB
D009271
CTDdecreases(activity)NOS2
D009271
CTDaffects(binding)OPRM1
D009271
CTDaffects(cotreatment)OPRM1
D009271
CTDdecreases(activity)OPRM1
D009271
CTDincreases(expression)OPRM1
D009271
CTDaffects(response to substance)OPRM1
D009271
CTDaffects(response to substance)SLC6A3
D009271
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