Tan Lab | DSigDB

Gene Set: D4 : CTD - Mycophenolic Acid

Collection

D4 : CTD

Chemical Name

Mycophenolic Acid ( From PubChem : MYCOPHENOLIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
320.337 g/mol	2	6	2.7332	True

Structure

InChI

InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+

InChIKey

HPNSFSBZBAHARI-RUDMXATFSA-N

Links

Gene (51 / 92)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ACRC		D009173
CTD	increases(expression)			AKT1		D009173
CTD	decreases(reaction)			ATF1		D009173
CTD	increases(phosphorylation)			ATF1		D009173
CTD	affects(cotreatment)			BAX		D009173
CTD	increases(expression)			BAX		D009173
CTD	affects(cotreatment)			BCL2		D009173
CTD	decreases(expression)			BCL2		D009173
CTD	decreases(expression)			BZRAP1		D009173
CTD	affects(cotreatment)			CASP3		D009173
CTD	increases(activity)			CASP3		D009173
CTD	increases(activity)			CASP3		D009173
CTD	decreases(expression)			CDKN1B		D009173
CTD	decreases(reaction)			CDKN1B		D009173
CTD	decreases(reaction)			CREB1		D009173
CTD	increases(phosphorylation)			CREB1		D009173
CTD	decreases(reaction)			CXCL8		D009173
CTD	increases(secretion)			CXCL8		D009173
CTD	increases(methylation)			CYP2C8		D009173
CTD	increases(methylation)			CYP3A4		D009173
CTD	increases(methylation)			CYP3A5		D009173
CTD	increases(expression)			FOS		D009173
CTD	decreases(reaction)			GSK3B		D009173
CTD	increases(phosphorylation)			GSK3B		D009173
CTD	decreases(expression)			HSPA5		D009173
CTD	decreases(expression)			IL2		D009173
CTD	decreases(reaction)			IL2		D009173
CTD	decreases(expression)			KLRK1		D009173
CTD	decreases(expression)			KRCC1		D009173
CTD	decreases(expression)			LRRC37A3		D009173
CTD	affects(cotreatment)			LYN		D009173
CTD	decreases(phosphorylation)			LYN		D009173
CTD	decreases(reaction)			MAPK1		D009173
CTD	increases(phosphorylation)			MAPK1		D009173
CTD	decreases(expression)			MAPK1		D009173
CTD	decreases(reaction)			MAPK3		D009173
CTD	increases(phosphorylation)			MAPK3		D009173
CTD	decreases(expression)			MAPK3		D009173
CTD	decreases(reaction)			MAPK8		D009173
CTD	increases(phosphorylation)			MAPK8		D009173
CTD	decreases(reaction)			MAPK9		D009173
CTD	increases(phosphorylation)			MAPK9		D009173
CTD	decreases(expression)			MAPT		D009173
CTD	increases(expression)			NANOS1		D009173
CTD	decreases(expression)			NCR1		D009173
CTD	decreases(expression)			NCR2		D009173
CTD	decreases(expression)			NCR3		D009173
CTD	increases(expression)			PDCD4		D009173
CTD	increases(expression)			PRKCA		D009173
CTD	decreases(reaction)			RELA		D009173
CTD	increases(phosphorylation)			RELA		D009173
CTD	increases(expression)			RGS2		D009173
CTD	affects(cotreatment)			RPS6		D009173
CTD	decreases(phosphorylation)			RPS6		D009173
CTD	decreases(expression)			SLC7A11		D009173
CTD	affects(cotreatment)			STAT5A		D009173
CTD	decreases(phosphorylation)			STAT5A		D009173
CTD	affects(metabolic processing)			UGT1A9		D009173
CTD	increases(glucuronidation)			UGT1A9		D009173
CTD	increases(expression)			ZBED8		D009173
PubChem	Potency-Replicate_1	uM	0.406	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.910	AR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.098	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.512	ESR1	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.473	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	None	uM		SMN1	-	GI(Protien) :
PubChem	Potency	uM	0.398	SMN2	-	GI(Protien) :
PubChem	Potency	uM	0.501	SMN2	-	GI(Protien) :
PubChem	Potency	uM	0.631	SMN2	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	0.033	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.114	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.114	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.150	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.184	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.299	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.366	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.376	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.581	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	12589.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Activity	-		PPARG	-	Target : CHEMBL235
ChEMBL	Activity	-		PPARG	-	Target : CHEMBL235
ChEMBL	Potency	nM	398.100	SMN1; SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	501.200	SMN1; SMN2	-	Target : CHEMBL1293232
ChEMBL	Potency	nM	631.000	SMN1; SMN2	-	Target : CHEMBL1293232

Download gene sets

gmt, text, Detailed text