Tan Lab | DSigDB

Gene Set: D4 : CTD - Mianserin

Collection

D4 : CTD

Chemical Name

Mianserin ( From PubChem : MIANSERIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
264.365 g/mol	0	2	3.0868	True

Structure

InChI

InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m0/s1

InChIKey

Links

Gene (16 / 38)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			FGF4		D008803
CTD	decreases(expression)			GSC		D008803
CTD	decreases(reaction)			HTR2C		D008803
CTD	increases(expression)			HTR2C		D008803
CTD	affects(activity)			HTR2C		D008803
CTD	affects(binding)			HTR2C		D008803
CTD	affects(binding)			HTR7		D008803
CTD	decreases(activity)			HTR7		D008803
CTD	decreases(reaction)			HTR7		D008803
CTD	increases(abundance)			HTR7		D008803
CTD	affects(binding)			HTR7		D008803
CTD	decreases(activity)			HTR7		D008803
CTD	decreases(reaction)			HTR7		D008803
CTD	decreases(expression)			ID2		D008803
CTD	decreases(expression)			PRKCA		D008803
CTD	decreases(reaction)			SLC22A2		D008803
CTD	increases(uptake)			SLC22A2		D008803
CTD	decreases(reaction)			SLC22A6		D008803
CTD	increases(uptake)			SLC22A6		D008803
CTD	decreases(localization)			SOX17		D008803
PubChem	Potency	uM	2.818	DRD1	-	GI(Protien) :
PubChem	Potency	uM	35.481	HSPA5	-	GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR6		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
ChEMBL	Potency	nM	2818.400	DRD1	-	Target : CHEMBL2056
ChEMBL	Activity	-		HTR3A	-	Target : CHEMBL1899
ChEMBL	Activity	-		HTR4	-	Target : CHEMBL1875

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