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Gene Set: D4 : CTD - Mexiletine

Collection D4 : CTD
Chemical Name Mexiletine ( From PubChem : MEXILETINE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotApprovedNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
179.259 g/mol 1 2 2.7297 True
Structure
InChI InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3/t10-/m1/s1
InChIKey VLPIATFUUWWMKC-SNVBAGLBSA-N
Links

Gene (7 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(cotreatment)IL1A
D008801
CTDincreases(response to substance)IL1A
D008801
CTDaffects(cotreatment)IL6
D008801
CTDincreases(response to substance)IL6
D008801
CTDdecreases(activity)KCNH2
D008801
CTDdecreases(reaction)SCN10A
D008801
CTDincreases(activity)SCN10A
D008801
CTDaffects(binding)SCN5A
D008801
CTDincreases(response to substance)SCN9A
D008801
CTDaffects(cotreatment)TNF
D008801
CTDincreases(response to substance)TNF
D008801
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