Tan Lab | DSigDB

Gene Set: D4 : CTD - Methylnitronitrosoguanidine

Collection

D4 : CTD

Chemical Name

Methylnitronitrosoguanidine ( From PubChem : 1-METHYL-3-NITRO-1-NITROSOGUANIDINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
147.093 g/mol	1	5	0.3295	True

Structure

InChI

InChI=1S/C2H5N5O3/c1-6(5-8)2(3)4-7(9)10/h1H3,(H2,3,4)

InChIKey

VZUNGTLZRAYYDE-UHFFFAOYSA-N

Links

Gene (132 / 150)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ADAM10		D008769
CTD	decreases(reaction)			AIFM1		D008769
CTD	increases(localization)			AIFM1		D008769
CTD	increases(expression)			ALPL		D008769
CTD	decreases(expression)			AMBP		D008769
CTD	increases(expression)			APC		D008769
CTD	increases(expression)			ARAF		D008769
CTD	decreases(expression)			ATP1B3		D008769
CTD	increases(expression)			AXL		D008769
CTD	increases(expression)			BAG1		D008769
CTD	affects(cotreatment)			BAK1		D008769
CTD	increases(response to substance)			BAK1		D008769
CTD	affects(cotreatment)			BAX		D008769
CTD	increases(response to substance)			BAX		D008769
CTD	affects(cotreatment)			BCL2L1		D008769
CTD	decreases(response to substance)			BCL2L1		D008769
CTD	increases(expression)			BIRC2		D008769
CTD	decreases(expression)			BMP4		D008769
CTD	increases(expression)			BRCA1		D008769
CTD	increases(expression)			BRCA2		D008769
CTD	increases(activity)			CASP3		D008769
CTD	increases(expression)			CASP4		D008769
CTD	increases(activity)			CASP9		D008769
CTD	decreases(expression)			CBX5		D008769
CTD	increases(expression)			CCNA1		D008769
CTD	increases(expression)			CCNH		D008769
CTD	increases(mutagenesis)			CD59		D008769
CTD	decreases(expression)			CDH8		D008769
CTD	increases(expression)			CDK5		D008769
CTD	decreases(expression)			CDKN1A		D008769
CTD	decreases(expression)			CKB		D008769
CTD	decreases(expression)			CXCR4		D008769
CTD	decreases(expression)			CYB561D2		D008769
CTD	increases(expression)			DAB2		D008769
CTD	decreases(expression)			DEAF1		D008769
CTD	increases(expression)			DEK		D008769
CTD	increases(expression)			DSTN		D008769
CTD	affects(localization)			DUT		D008769
CTD	increases(secretion)			DUT		D008769
CTD	affects(activity)			EGF		D008769
CTD	decreases(reaction)			EGF		D008769
CTD	increases(activity)			EGF		D008769
CTD	increases(phosphorylation)			EGF		D008769
CTD	affects(localization)			EGFR		D008769
CTD	decreases(reaction)			EGFR		D008769
CTD	increases(phosphorylation)			EGFR		D008769
CTD	increases(expression)			EIF3E		D008769
CTD	decreases(expression)			EIF5		D008769
CTD	increases(expression)			ELK3		D008769
CTD	increases(expression)			EMP1		D008769
CTD	increases(expression)			EPCAM		D008769
CTD	increases(expression)			EPHA1		D008769
CTD	decreases(expression)			EPHB3		D008769
CTD	increases(expression)			ERBB2		D008769
CTD	increases(expression)			ERBB4		D008769
CTD	increases(expression)			ETS1		D008769
CTD	increases(expression)			FASN		D008769
CTD	decreases(expression)			FCGRT		D008769
CTD	increases(expression)			FES		D008769
CTD	increases(expression)			FGFR1OP		D008769
CTD	decreases(expression)			FOSL1		D008769
CTD	increases(expression)			FYN		D008769
CTD	increases(expression)			GDF15		D008769
CTD	decreases(expression)			GSS		D008769
CTD	decreases(expression)			HIST1H4B		D008769
CTD	increases(expression)			HLA-DRB1		D008769
CTD	increases(expression)			HMGB1		D008769
CTD	decreases(expression)			HMGB2		D008769
CTD	decreases(reaction)			HRAS		D008769
CTD	increases(activity)			HRAS		D008769
CTD	increases(expression)			HSP90B1		D008769
CTD	decreases(response to substance)			ICAM1		D008769
CTD	increases(expression)			ICAM1		D008769
CTD	decreases(reaction)			ICAM1		D008769
CTD	decreases(expression)			ID1		D008769
CTD	increases(expression)			IFITM1		D008769
CTD	increases(expression)			IFRD1		D008769
CTD	decreases(expression)			ITGB4		D008769
CTD	increases(expression)			KIT		D008769
CTD	decreases(expression)			KRT17		D008769
CTD	increases(expression)			LGALS8		D008769
CTD	decreases(expression)			LIG1		D008769
CTD	increases(phosphorylation)			MAPK14		D008769
CTD	increases(expression)			MAPK4		D008769
CTD	increases(phosphorylation)			MAPK8		D008769
CTD	increases(expression)			MAPK9		D008769
CTD	increases(expression)			MAX		D008769
CTD	increases(expression)			MCAM		D008769
CTD	decreases(expression)			MCM2		D008769
CTD	decreases(expression)			MCM4		D008769
CTD	increases(expression)			MDM2		D008769
CTD	increases(expression)			MECOM		D008769
CTD	increases(expression)			MET		D008769
CTD	decreases(response to substance)			MGMT		D008769
CTD	decreases(expression)			MGST2		D008769
CTD	decreases(expression)			MLH1		D008769
CTD	increases(response to substance)			MPG		D008769
CTD	increases(expression)			MSH2		D008769
CTD	increases(expression)			MYBL1		D008769
CTD	increases(expression)			MYL2		D008769
CTD	increases(expression)			MYL9		D008769
CTD	decreases(expression)			MYLK		D008769
CTD	decreases(expression)			NBL1		D008769
CTD	increases(degradation)			NFKBIA		D008769
CTD	increases(phosphorylation)			NFKBIA		D008769
CTD	increases(response to substance)			PARP1		D008769
CTD	decreases(expression)			PCDH7		D008769
CTD	decreases(expression)			PCNA		D008769
CTD	increases(expression)			PDGFB		D008769
CTD	increases(expression)			PEA15		D008769
CTD	increases(expression)			PGK1		D008769
CTD	increases(expression)			PLXNA3		D008769
CTD	increases(expression)			PRKD1		D008769
CTD	increases(expression)			PTP4A1		D008769
CTD	decreases(expression)			PTPRA		D008769
CTD	decreases(expression)			PTPRG		D008769
CTD	decreases(expression)			PTPRS		D008769
CTD	decreases(expression)			RAD23A		D008769
CTD	decreases(expression)			RARRES3		D008769
CTD	increases(expression)			RBBP5		D008769
CTD	increases(expression)			RBM6		D008769
CTD	increases(expression)			RPSA		D008769
CTD	increases(expression)			RRM2B		D008769
CTD	increases(expression)			SERPING1		D008769
CTD	decreases(expression)			SMAD2		D008769
CTD	increases(expression)			SNORA62		D008769
CTD	increases(expression)			SNRPN		D008769
CTD	decreases(expression)			SPARC		D008769
CTD	increases(expression)			SPINK1		D008769
CTD	decreases(expression)			SPINT2		D008769
CTD	increases(expression)			SPINT2		D008769
CTD	increases(expression)			SQLE		D008769
CTD	decreases(expression)			SRSF7		D008769
CTD	decreases(expression)			STK39		D008769
CTD	increases(expression)			TBRG4		D008769
CTD	increases(expression)			TIAM1		D008769
CTD	increases(expression)			TNC		D008769
CTD	increases(expression)			TNFRSF25		D008769
CTD	increases(expression)			TP53		D008769
CTD	decreases(response to substance)			TP53		D008769
CTD	increases(response to substance)			TP53		D008769
CTD	increases(expression)			TRAM1		D008769
CTD	decreases(expression)			TSC22D1		D008769
CTD	increases(expression)			UCHL1		D008769
CTD	increases(expression)			VIM		D008769
CTD	decreases(expression)			WARS		D008769
CTD	increases(expression)			WNT2		D008769
PubChem	Potency-Replicate_1	uM	68.171	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	34.167	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	43.013	ESR1	-	GI(Protien) :

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