Tan Lab | DSigDB

Gene Set: D4 : CTD - Methyl Parathion

Collection

D4 : CTD

Chemical Name

Methyl Parathion ( From PubChem : METHYL PARATHION )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
263.207 g/mol	0	4	3.6647	True

Structure

InChI

InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

InChIKey

RLBIQVVOMOPOHC-UHFFFAOYSA-N

Links

Gene (23 / 56)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			ACHE		D008743
CTD	decreases(activity)			ACHE		D008743
CTD	affects(cotreatment)			ACHE		D008743
CTD	decreases(activity)			ACHE		D008743
CTD	decreases(activity)			ACHE		D008743
CTD	affects(cotreatment)			AKR1C1		D008743
CTD	affects(response to substance)			AKR1C1		D008743
CTD	increases(activity)			AKR1C1		D008743
CTD	increases(reaction)			AKR1C1		D008743
CTD	increases(expression)			AKR1C1		D008743
CTD	affects(cotreatment)			AKR1C2		D008743
CTD	affects(response to substance)			AKR1C2		D008743
CTD	increases(activity)			AKR1C2		D008743
CTD	increases(reaction)			AKR1C2		D008743
CTD	increases(expression)			AKR1C2		D008743
CTD	affects(binding)			ALB		D008743
CTD	decreases(reaction)			AR		D008743
CTD	increases(activity)			AR		D008743
CTD	decreases(reaction)			AR		D008743
CTD	increases(activity)			AR		D008743
CTD	affects(cotreatment)			BCHE		D008743
CTD	decreases(activity)			BCHE		D008743
CTD	increases(expression)			CDKN1A		D008743
CTD	increases(activity)			CYP19A1		D008743
CTD	decreases(reaction)			CYP1A1		D008743
CTD	increases(expression)			CYP1A1		D008743
CTD	increases(expression)			GADD45A		D008743
CTD	affects(metabolic processing)			GSTA1		D008743
CTD	decreases(alkylation)			GSTA1		D008743
CTD	increases(expression)			GSTA1		D008743
CTD	affects(metabolic processing)			GSTT1		D008743
CTD	decreases(alkylation)			GSTT1		D008743
CTD	decreases(reaction)			LCAT		D008743
CTD	increases(chemical synthesis)			LCAT		D008743
CTD	increases(metabolic processing)			LCAT		D008743
CTD	decreases(activity)			LCAT		D008743
CTD	increases(expression)			MDM2		D008743
CTD	decreases(expression)			MKI67		D008743
CTD	increases(expression)			TP53		D008743
PubChem	AhR Potency (uM)	uM	34.376	AHR	-	GI(Protien) :
PubChem	Potency	uM	19.953	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.607	ESR1	-	GI(Protien) :
PubChem	Potency	uM	2.909	TDP1	-	GI(Protien) :
PubChem	Potency	uM	5.805	TDP1	-	GI(Protien) :
PubChem	Potency	uM	3.981	THRB	-	GI(Protien) :
PubChem	Potency	uM	14.125	THRB	-	GI(Protien) :
PubChem	Potency	uM	25.119	THRB	-	GI(Protien) :
PubChem	Potency	uM	31.623	THRB	-	GI(Protien) :
PubChem	Potency	uM	15.849	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	19952.600	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	3981.100	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	25118.900	THRB	-	Target : CHEMBL1947
ChEMBL	Potency	nM	31622.800	THRB	-	Target : CHEMBL1947
ChEMBL	Potency	nM	14125.400	THRB	-	Target : CHEMBL1947
ChEMBL	Potency	nM	3981.100	THRB	-	Target : CHEMBL1947

Download gene sets

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