Tan Lab | DSigDB

Gene Set: D4 : CTD - Methoprene

Collection

D4 : CTD

Chemical Name

Methoprene ( From PubChem : METHOPRENE (RACEMATE) )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
310.471 g/mol	0	3	5.062	False(3/4)

Structure

InChI

InChI=1S/C19H34O3/c1-15(2)22-18(20)14-17(4)11-8-10-16(3)12-9-13-19(5,6)21-7/h8,11,14-16H,9-10,12-13H2,1-7H3/b11-8+,17-14+/t16-/m1/s1

InChIKey

Links

Gene (9 / 18)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			RXRA		D008726
CTD	increases(activity)			RXRA		D008726
CTD	affects(binding)			RXRB		D008726
CTD	increases(activity)			RXRB		D008726
PubChem	Ratio Potency (uM)	uM	37.431	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	68.590	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.541	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	35.822	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	60.137	AHR	-	GI(Protien) :
PubChem	Potency	uM	48.558	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	64.935	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	66.824	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	31.623	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.986	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	50.119	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	15848.900	TDP1	-	Target : CHEMBL1075138

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