Tan Lab | DSigDB

Gene Set: D4 : CTD - Methadone

Collection

D4 : CTD

Chemical Name

Methadone ( From PubChem : METHADONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Not	Approved	Not	Not	2

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
309.445 g/mol	0	2	4.292	True

Structure

InChI

InChI=1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3/t17-/m1/s1

InChIKey

Links

Gene (17 / 25)

⊖ Less

Source	Type	Gene	Other
CTD	affects(activity)	ABCB1	D008691
CTD	increases(expression)	ABCB1	D008691
CTD	affects(localization)	BAX	D008691
CTD	affects(localization)	CYCS	D008691
CTD	affects(metabolic processing)	CYP19A1	D008691
CTD	decreases(reaction)	CYP19A1	D008691
CTD	affects(metabolic processing)	CYP3A4	D008691
CTD	decreases(expression)	IL2	D008691
CTD	decreases(reaction)	IL4	D008691
CTD	increases(expression)	IL4	D008691
CTD	decreases(response to substance)	INS	D008691
CTD	decreases(activity)	KCNH2	D008691
CTD	increases(reaction)	KCNH2	D008691
CTD	increases(expression)	LEP	D008691
CTD	increases(phosphorylation)	MAPK1	D008691
CTD	increases(phosphorylation)	MAPK3	D008691
CTD	increases(expression)	NFKBIA	D008691
CTD	affects(binding)	ORM2	D008691
CTD	decreases(reaction)	ORM2	D008691
CTD	increases(activity)	PLD2	D008691
CTD	affects(secretion)	PRL	D008691
CTD	increases(expression)	PRL	D008691
CTD	increases(secretion)	PRL	D008691
CTD	affects(binding)	TLR4	D008691
CTD	affects(reaction)	TLR4	D008691

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