Tan Lab | DSigDB

Gene Set: D4 : CTD - Melitten

Collection

D4 : CTD

Chemical Name

Melitten ( From PubChem : MELITTEN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
2846.46 g/mol	41	69	7.5198	False(0/4)

Structure

InChI

InChI=1S/C131H229N39O31/c1-23-71(16)102(163-97(176)60-135)122(194)146-62-98(177)148-74(19)109(181)164-100(69(12)13)124(196)160-88(55-65(4)5)116(188)155-84(41-30-33-51-134)115(187)165-101(70(14)15)125(197)161-90(57-67(8)9)118(190)168-106(77(22)173)128(200)169-105(76(21)172)123(195)147-63-99(178)150-92(58-68(10)11)129(201)170-54-36-44-94(170)121(193)149-75(20)108(180)158-89(56-66(6)7)117(189)166-104(73(18)25-3)127(199)162-93(64-171)120(192)159-91(59-78-61-145-80-38-27-26-37-79(78)80)119(191)167-103(72(17)24-2)126(198)157-83(40-29-32-50-133)111(183)154-85(42-34-52-143-130(139)140)112(184)152-82(39-28-31-49-132)110(182)153-86(43-35-53-144-131(141)142)113(185)156-87(46-48-96(137)175)114(186)151-81(107(138)179)45-47-95(136)174/h26-27,37-38,61,65-77,81-94,100-106,145,171-173H,23-25,28-36,39-60,62-64,132-135H2,1-22H3,(H2,136,174)(H2,137,175)(H2,138,179)(H,146,194)(H,147,195)(H,148,177)(H,149,193)(H,150,178)(H,151,186)(H,152,184)(H,153,182)(H,154,183)(H,155,188)(H,156,185)(H,157,198)(H,158,180)(H,159,192)(H,160,196)(H,161,197)(H,162,199)(H,163,176)(H,164,181)(H,165,187)(H,166,189)(H,167,191)(H,168,190)(H,169,200)(H4,139,140,143)(H4,141,142,144)

InChIKey

VDXZNPDIRNWWCW-UHFFFAOYSA-N

Links

Gene (53 / 168)

⊖ Less

Source	Type	Gene	Other
CTD	increases(activity)	ADAM10	D008555
CTD	increases(cleavage)	ADAM10	D008555
CTD	increases(activity)	ADAM17	D008555
CTD	increases(cleavage)	ADAM17	D008555
CTD	increases(expression)	AIM2	D008555
CTD	increases(reaction)	AIM2	D008555
CTD	decreases(reaction)	AKT1	D008555
CTD	increases(phosphorylation)	AKT1	D008555
CTD	increases(activity)	ALOX5	D008555
CTD	increases(expression)	BAX	D008555
CTD	decreases(expression)	BCL2	D008555
CTD	decreases(expression)	BIRC3	D008555
CTD	increases(activity)	CASP3	D008555
CTD	increases(cleavage)	CASP3	D008555
CTD	increases(expression)	CASP3	D008555
CTD	increases(expression)	CASP8	D008555
CTD	increases(activity)	CASP9	D008555
CTD	increases(cleavage)	CASP9	D008555
CTD	increases(secretion)	CDH1	D008555
CTD	affects(binding)	CGB	D008555
CTD	increases(response to substance)	CGB	D008555
CTD	decreases(reaction)	CHUK	D008555
CTD	increases(activity)	CHUK	D008555
CTD	increases(phosphorylation)	CHUK	D008555
CTD	decreases(localization)	CHUK	D008555
CTD	increases(expression)	CXCL8	D008555
CTD	affects(binding)	DRD2	D008555
CTD	decreases(reaction)	DRD2	D008555
CTD	increases(activity)	EGFR	D008555
CTD	increases(expression)	FAS	D008555
CTD	increases(expression)	FAS	D008555
CTD	decreases(expression)	FGF2	D008555
CTD	affects(binding)	GNRH1	D008555
CTD	increases(response to substance)	GNRH1	D008555
CTD	decreases(reaction)	HTR1A	D008555
CTD	increases(abundance)	HTR1A	D008555
CTD	decreases(expression)	ICAM1	D008555
CTD	decreases(reaction)	IKBKB	D008555
CTD	increases(activity)	IKBKB	D008555
CTD	increases(expression)	IL18	D008555
CTD	increases(reaction)	IL18	D008555
CTD	increases(expression)	IL1B	D008555
CTD	increases(reaction)	IL1B	D008555
CTD	decreases(phosphorylation)	JAK2	D008555
CTD	decreases(reaction)	JUN	D008555
CTD	increases(localization)	JUN	D008555
CTD	decreases(expression)	KDR	D008555
CTD	affects(binding)	LHCGR	D008555
CTD	increases(response to substance)	LHCGR	D008555
CTD	decreases(reaction)	MAPK1	D008555
CTD	increases(activity)	MAPK1	D008555
CTD	increases(phosphorylation)	MAPK1	D008555
CTD	decreases(reaction)	MAPK1	D008555
CTD	increases(phosphorylation)	MAPK1	D008555
CTD	decreases(phosphorylation)	MAPK1	D008555
CTD	increases(activity)	MAPK1	D008555
CTD	increases(phosphorylation)	MAPK1	D008555
CTD	increases(phosphorylation)	MAPK1	D008555
CTD	decreases(reaction)	MAPK3	D008555
CTD	increases(activity)	MAPK3	D008555
CTD	increases(phosphorylation)	MAPK3	D008555
CTD	decreases(reaction)	MAPK3	D008555
CTD	increases(phosphorylation)	MAPK3	D008555
CTD	decreases(phosphorylation)	MAPK3	D008555
CTD	increases(activity)	MAPK3	D008555
CTD	increases(phosphorylation)	MAPK3	D008555
CTD	increases(phosphorylation)	MAPK3	D008555
CTD	decreases(reaction)	MMP2	D008555
CTD	increases(secretion)	MMP2	D008555
CTD	decreases(reaction)	MMP3	D008555
CTD	increases(expression)	MMP3	D008555
CTD	decreases(reaction)	MMP9	D008555
CTD	increases(activity)	MMP9	D008555
CTD	increases(expression)	MMP9	D008555
CTD	decreases(reaction)	MMP9	D008555
CTD	increases(expression)	MMP9	D008555
CTD	increases(secretion)	MMP9	D008555
CTD	decreases(reaction)	MMP9	D008555
CTD	increases(expression)	MMP9	D008555
CTD	increases(secretion)	MMP9	D008555
CTD	decreases(reaction)	NFKB1	D008555
CTD	increases(localization)	NFKB1	D008555
CTD	decreases(reaction)	NFKB1	D008555
CTD	increases(activity)	NFKB1	D008555
CTD	increases(localization)	NFKB1	D008555
CTD	decreases(localization)	NFKB1	D008555
CTD	decreases(reaction)	NFKB1	D008555
CTD	increases(phosphorylation)	NFKB1	D008555
CTD	decreases(localization)	NFKB1	D008555
CTD	decreases(reaction)	NFKBIA	D008555
CTD	increases(phosphorylation)	NFKBIA	D008555
CTD	decreases(reaction)	NFKBIA	D008555
CTD	increases(phosphorylation)	NFKBIA	D008555
CTD	decreases(reaction)	NFKBIA	D008555
CTD	increases(phosphorylation)	NFKBIA	D008555
CTD	decreases(localization)	NFKBIA	D008555
CTD	decreases(reaction)	NFKBIA	D008555
CTD	increases(phosphorylation)	NFKBIA	D008555
CTD	decreases(reaction)	NFKBIA	D008555
CTD	increases(degradation)	NFKBIA	D008555
CTD	decreases(reaction)	NOS2	D008555
CTD	increases(chemical synthesis)	NOS2	D008555
CTD	increases(expression)	NOS2	D008555
CTD	decreases(reaction)	NOS2	D008555
CTD	increases(chemical synthesis)	NOS2	D008555
CTD	increases(expression)	NOS2	D008555
CTD	decreases(expression)	NOS2	D008555
CTD	increases(activity)	P2RX7	D008555
CTD	increases(response to substance)	P2RX7	D008555
CTD	decreases(expression)	PLA2G4A	D008555
CTD	decreases(reaction)	PTGS2	D008555
CTD	increases(chemical synthesis)	PTGS2	D008555
CTD	increases(expression)	PTGS2	D008555
CTD	decreases(reaction)	PTGS2	D008555
CTD	increases(chemical synthesis)	PTGS2	D008555
CTD	increases(expression)	PTGS2	D008555
CTD	decreases(expression)	PTGS2	D008555
CTD	decreases(chemical synthesis)	PTGS2	D008555
CTD	decreases(expression)	PTGS2	D008555
CTD	increases(expression)	PTGS2	D008555
CTD	decreases(reaction)	PTGS2	D008555
CTD	affects(cotreatment)	RAB11A	D008555
CTD	decreases(localization)	RAB11A	D008555
CTD	affects(cotreatment)	RAB5A	D008555
CTD	decreases(localization)	RAB5A	D008555
CTD	increases(localization)	RAB5A	D008555
CTD	decreases(activity)	RAC1	D008555
CTD	decreases(reaction)	RELA	D008555
CTD	increases(localization)	RELA	D008555
CTD	decreases(reaction)	RELA	D008555
CTD	increases(localization)	RELA	D008555
CTD	affects(localization)	RELA	D008555
CTD	decreases(reaction)	RELA	D008555
CTD	decreases(localization)	RELA	D008555
CTD	decreases(reaction)	SLC6A3	D008555
CTD	increases(localization)	SLC6A3	D008555
CTD	affects(binding)	SLC6A3	D008555
CTD	decreases(reaction)	SLC6A3	D008555
CTD	increases(uptake)	SLC6A3	D008555
CTD	affects(cotreatment)	SLC6A3	D008555
CTD	increases(localization)	SLC6A3	D008555
CTD	decreases(phosphorylation)	STAT3	D008555
CTD	affects(reaction)	STAT3	D008555
CTD	increases(secretion)	TGFA	D008555
CTD	affects(localization)	TNF	D008555
CTD	decreases(reaction)	TNF	D008555
CTD	increases(degradation)	TNF	D008555
CTD	increases(expression)	TNF	D008555
CTD	increases(phosphorylation)	TNF	D008555
CTD	decreases(reaction)	TNF	D008555
CTD	increases(phosphorylation)	TNF	D008555
CTD	increases(secretion)	TNF	D008555
CTD	increases(expression)	TNFRSF10A	D008555
CTD	affects(reaction)	TNFRSF10A	D008555
CTD	decreases(phosphorylation)	TNFRSF10A	D008555
CTD	affects(response to substance)	TNFRSF10A	D008555
CTD	increases(expression)	TNFRSF21	D008555
CTD	affects(reaction)	TNFRSF21	D008555
CTD	decreases(phosphorylation)	TNFRSF21	D008555
CTD	affects(response to substance)	TNFRSF21	D008555
CTD	increases(expression)	TNFRSF25	D008555
CTD	affects(reaction)	TNFRSF25	D008555
CTD	decreases(phosphorylation)	TNFRSF25	D008555
CTD	affects(response to substance)	TNFRSF25	D008555
CTD	decreases(expression)	VEGFA	D008555
CTD	decreases(expression)	VEGFA	D008555
CTD	decreases(reaction)	VEGFA	D008555
CTD	decreases(expression)	XIAP	D008555

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