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Gene Set: D4 : CTD - Melarsoprol

Collection D4 : CTD
Chemical Name Melarsoprol ( From PubChem : MELARSOPROL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
398.339 g/mol 4 8 1.5511 True
Structure
InChI InChI=1S/C12H15AsN6OS2/c14-10-17-11(15)19-12(18-10)16-8-3-1-7(2-4-8)13-21-6-9(5-20)22-13/h1-4,9,20H,5-6H2,(H5,14,15,16,17,18,19)
InChIKey JCYZMTMYPZHVBF-UHFFFAOYSA-N
Links

Gene (10 / 13)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(expression)BCL2
D008549
CTDincreases(activity)CASP3
D008549
CTDdecreases(activity)CYP2C19
D008549
CTDdecreases(activity)CYP2C9
D008549
CTDdecreases(activity)CYP2D6
D008549
CTDdecreases(activity)CYP3A4
D008549
CTDaffects(binding)NFKB1
D008549
CTDdecreases(reaction)NFKB1
D008549
CTDincreases(cleavage)PARP1
D008549
CTDaffects(binding)RELA
D008549
CTDdecreases(reaction)RELA
D008549
CTDdecreases(expression)RIPK1
D008549
CTDincreases(cleavage)RIPK1
D008549
Download gene sets gmt, text, Detailed text
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