Tan Lab | DSigDB

Gene Set: D4 : CTD - Medroxyprogesterone

Collection

D4 : CTD

Chemical Name

Medroxyprogesterone ( From PubChem : MEDROXYPROGESTERONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Approved	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
344.488 g/mol	1	3	4.0844	True

Structure

InChI

InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1

InChIKey

FRQMUZJSZHZSGN-HBNHAYAOSA-N

Links

Gene (10 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(activity)			CAT		D008525
CTD	affects(cotreatment)			CAT		D008525
CTD	decreases(activity)			CYP2C8		D008525
CTD	affects(cotreatment)			FSHB		D008525
CTD	affects(expression)			FSHB		D008525
CTD	affects(cotreatment)			LPO		D008525
CTD	affects(expression)			LPO		D008525
CTD	decreases(reaction)			SLC22A2		D008525
CTD	increases(uptake)			SLC22A2		D008525
PubChem	Ratio Potency (uM)	uM	0.001	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.002	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.067	AR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.085	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.125	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	29.093	TDP1	-	GI(Protien) :

Download gene sets

gmt, text, Detailed text