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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Manganese

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Collection	D4 : CTD
Chemical Name	Manganese ( From PubChem : MANGANESE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 54.938 g/mol 0 0 0.0 True
Structure
InChI	InChI=1S/Mn
InChIKey	PWHULOQIROXLJO-UHFFFAOYSA-N
Links
Gene (213 / 257) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(expression) ABCA5 D008345 CTD increases(expression) ABCA9 D008345 CTD increases(expression) ABI2 D008345 CTD increases(activity) ACO1 D008345 CTD decreases(activity) ACO2 D008345 CTD decreases(reaction) ACO2 D008345 CTD decreases(expression) ACO2 D008345 CTD increases(expression) ADM D008345 CTD decreases(expression) AKAP7 D008345 CTD decreases(expression) AKT1 D008345 CTD increases(expression) ANGPTL4 D008345 CTD increases(expression) AP3B2 D008345 CTD increases(expression) APOL1 D008345 CTD increases(expression) APOL2 D008345 CTD increases(expression) APP D008345 CTD affects(binding) ARG1 D008345 CTD decreases(expression) ARHGDIA D008345 CTD increases(expression) ARHGEF4 D008345 CTD decreases(expression) ATF6 D008345 CTD decreases(expression) ATM D008345 CTD affects(response to substance) ATP13A2 D008345 CTD increases(phosphorylation) ATP7B D008345 CTD decreases(expression) ATP8A1 D008345 CTD increases(expression) BACE1 D008345 CTD decreases(expression) BUB1 D008345 CTD increases(expression) C8ORF4 D008345 CTD increases(expression) CALCOCO2 D008345 CTD increases(activity) CASP3 D008345 CTD increases(expression) CCL7 D008345 CTD decreases(expression) CCNB2 D008345 CTD increases(expression) CD48 D008345 CTD increases(expression) CD8B D008345 CTD decreases(expression) CDKN2C D008345 CTD decreases(expression) CDKN3 D008345 CTD increases(expression) CEBPD D008345 CTD increases(expression) CELSR1 D008345 CTD decreases(expression) CEP128 D008345 CTD decreases(expression) CKS2 D008345 CTD decreases(expression) CNOT2 D008345 CTD increases(expression) CNOT6L D008345 CTD decreases(expression) COL12A1 D008345 CTD decreases(expression) CPM D008345 CTD increases(expression) CR1 D008345 CTD decreases(expression) CTNNA1 D008345 CTD decreases(expression) CTNNB1 D008345 CTD increases(expression) CXCL14 D008345 CTD increases(expression) CXCL2 D008345 CTD increases(expression) CXCL3 D008345 CTD increases(expression) CXCL6 D008345 CTD increases(secretion) CXCL8 D008345 CTD decreases(response to substance) CYP2D6 D008345 CTD increases(expression) DACH2 D008345 CTD decreases(expression) DAZ2 D008345 CTD increases(expression) DDIT3 D008345 CTD decreases(expression) DNAH14 D008345 CTD decreases(expression) DNPH1 D008345 CTD increases(expression) DPP4 D008345 CTD decreases(expression) DR1 D008345 CTD increases(expression) DSPP D008345 CTD increases(expression) EIF2A D008345 CTD decreases(expression) ELF1 D008345 CTD increases(expression) EML2 D008345 CTD increases(glycosylation) EPO D008345 CTD decreases(expression) ERCC6L D008345 CTD increases(expression) EREG D008345 CTD increases(expression) ERICH1 D008345 CTD decreases(expression) EXOC6 D008345 CTD decreases(expression) EYA4 D008345 CTD decreases(expression) FANCF D008345 CTD decreases(expression) FHL1 D008345 CTD increases(expression) FLCN D008345 CTD affects(binding) FOS D008345 CTD increases(activity) FOS D008345 CTD increases(reaction) FOS D008345 CTD increases(expression) FOS D008345 CTD decreases(expression) FOS D008345 CTD increases(expression) FOXP2 D008345 CTD increases(expression) FXYD2 D008345 CTD increases(expression) GABRG2 D008345 CTD increases(expression) GAL D008345 CTD decreases(expression) GCFC2 D008345 CTD increases(expression) GDAP2 D008345 CTD increases(expression) GDF15 D008345 CTD decreases(expression) GSR D008345 CTD decreases(expression) GTF2H1 D008345 CTD increases(expression) HEPH D008345 CTD increases(activity) HIF1A D008345 CTD increases(expression) HIF1A D008345 CTD increases(expression) HIF1A D008345 CTD decreases(expression) HIF1AN D008345 CTD increases(expression) HLA-DRB4 D008345 CTD increases(expression) HMOX1 D008345 CTD decreases(expression) HOXB9 D008345 CTD increases(expression) HSPA5 D008345 CTD affects(binding) HSPA8 D008345 CTD increases(expression) HSPA8 D008345 CTD increases(expression) ID2 D008345 CTD affects(binding) IDH3A D008345 CTD affects(binding) IDH3G D008345 CTD increases(expression) IL12A D008345 CTD increases(expression) IL2 D008345 CTD increases(reaction) IL2 D008345 CTD increases(secretion) IL6 D008345 CTD increases(expression) IL7 D008345 CTD decreases(expression) IPO11 D008345 CTD increases(expression) ITGA3 D008345 CTD increases(expression) ITGB5 D008345 CTD affects(binding) ITIH1 D008345 CTD increases(reaction) ITIH1 D008345 CTD affects(binding) ITIH2 D008345 CTD increases(reaction) ITIH2 D008345 CTD affects(binding) JUN D008345 CTD increases(activity) JUN D008345 CTD increases(reaction) JUN D008345 CTD increases(expression) JUN D008345 CTD increases(phosphorylation) JUN D008345 CTD decreases(expression) JUN D008345 CTD increases(expression) KCNIP3 D008345 CTD increases(expression) KCNJ3 D008345 CTD increases(expression) KLF4 D008345 CTD decreases(expression) KLF9 D008345 CTD increases(expression) LCE2B D008345 CTD decreases(expression) LEFTY2 D008345 CTD decreases(abundance) LEP D008345 CTD increases(expression) LMAN2 D008345 CTD increases(response to substance) LRRK2 D008345 CTD affects(cotreatment) LRRK2 D008345 CTD decreases(reaction) MAPK1 D008345 CTD increases(phosphorylation) MAPK1 D008345 CTD decreases(phosphorylation) MAPK1 D008345 CTD increases(phosphorylation) MAPK1 D008345 CTD decreases(phosphorylation) MAPK14 D008345 CTD decreases(reaction) MAPK3 D008345 CTD increases(phosphorylation) MAPK3 D008345 CTD decreases(phosphorylation) MAPK3 D008345 CTD increases(phosphorylation) MAPK3 D008345 CTD increases(phosphorylation) MAPK8 D008345 CTD increases(phosphorylation) MAPK9 D008345 CTD increases(reaction) MAPK9 D008345 CTD increases(phosphorylation) MAPK9 D008345 CTD increases(expression) MBP D008345 CTD increases(expression) MCHR1 D008345 CTD decreases(expression) MCM4 D008345 CTD decreases(expression) MCM5 D008345 CTD increases(expression) ME3 D008345 CTD increases(expression) MIA D008345 CTD decreases(expression) MMP14 D008345 CTD decreases(expression) MMP2 D008345 CTD decreases(expression) MSH6 D008345 CTD decreases(expression) MTM1 D008345 CTD decreases(phosphorylation) MTOR D008345 CTD increases(phosphorylation) MTOR D008345 CTD increases(expression) MYCNOS D008345 CTD increases(expression) MYOM1 D008345 CTD increases(expression) MYT1L D008345 CTD increases(expression) NAMPT D008345 CTD increases(expression) NDRG1 D008345 CTD increases(expression) NFIB D008345 CTD decreases(expression) NFIX D008345 CTD decreases(expression) NFYB D008345 CTD affects(binding) NMT1 D008345 CTD decreases(activity) NMT1 D008345 CTD decreases(reaction) NOS3 D008345 CTD increases(activity) NOS3 D008345 CTD increases(phosphorylation) NOS3 D008345 CTD decreases(expression) NOTCH4 D008345 CTD decreases(expression) NPPA D008345 CTD increases(expression) NRG2 D008345 CTD increases(expression) NRP1 D008345 CTD decreases(expression) NUCKS1 D008345 CTD decreases(reaction) NUDT9 D008345 CTD increases(activity) NUDT9 D008345 CTD increases(reaction) NUDT9 D008345 CTD increases(expression) OLFM1 D008345 CTD increases(expression) PAPPA D008345 CTD affects(response to substance) PARK2 D008345 CTD decreases(transport) PARK2 D008345 CTD increases(expression) PCDH7 D008345 CTD increases(expression) PCDHA6 D008345 CTD increases(expression) PDK1 D008345 CTD increases(expression) PGF D008345 CTD decreases(expression) PHTF1 D008345 CTD increases(expression) PLCE1 D008345 CTD decreases(expression) PLN D008345 CTD increases(expression) POU1F1 D008345 CTD decreases(expression) PRIM1 D008345 CTD decreases(expression) PRIM2 D008345 CTD increases(expression) PRKD1 D008345 CTD decreases(expression) PRL D008345 CTD increases(expression) PTGS2 D008345 CTD decreases(expression) PTK2B D008345 CTD increases(expression) PTX3 D008345 CTD decreases(expression) PVR D008345 CTD decreases(expression) RAB21 D008345 CTD decreases(expression) RAB23 D008345 CTD decreases(expression) RFC5 D008345 CTD increases(expression) RGS2 D008345 CTD decreases(expression) RGS5 D008345 CTD increases(expression) RGS6 D008345 CTD increases(expression) RNF145 D008345 CTD increases(expression) S100A6 D008345 CTD increases(expression) SCN3B D008345 CTD decreases(expression) SDCBP2 D008345 CTD increases(expression) SFTPB D008345 CTD increases(expression) SFXN5 D008345 CTD increases(expression) SIRT2 D008345 CTD increases(expression) SIX3 D008345 CTD increases(expression) SLC11A2 D008345 CTD increases(uptake) SLC11A2 D008345 CTD increases(expression) SLC11A2 D008345 CTD increases(expression) SLC16A3 D008345 CTD decreases(expression) SLC22A15 D008345 CTD increases(expression) SLC2A13 D008345 CTD increases(expression) SLC38A10 D008345 CTD decreases(expression) SLC4A10 D008345 CTD affects(cotreatment) SLC6A3 D008345 CTD increases(response to substance) SLC6A3 D008345 CTD affects(localization) SLC6A3 D008345 CTD increases(response to substance) SLC6A3 D008345 CTD increases(expression) SMIM14 D008345 CTD increases(activity) SOD2 D008345 CTD increases(expression) SOD2 D008345 CTD decreases(expression) SORT1 D008345 CTD decreases(expression) SPA17 D008345 CTD affects(binding) SRC D008345 CTD decreases(expression) SRC D008345 CTD decreases(expression) STOX1 D008345 CTD increases(reaction) SULT1A3 D008345 CTD increases(sulfation) SULT1A3 D008345 CTD increases(expression) SULT1C2 D008345 CTD affects(binding) TAB1 D008345 CTD decreases(expression) TACR1 D008345 CTD decreases(expression) TAGLN2 D008345 CTD increases(expression) TBX18 D008345 CTD affects(binding) TF D008345 CTD decreases(uptake) TF D008345 CTD affects(binding) TF D008345 CTD increases(expression) TFAP2B D008345 CTD decreases(expression) TGFBR1 D008345 CTD affects(binding) TNFAIP6 D008345 CTD increases(reaction) TNFAIP6 D008345 CTD increases(expression) TNFRSF25 D008345 CTD increases(expression) TNRC6A D008345 CTD increases(expression) TPCN1 D008345 CTD increases(expression) TRPM1 D008345 CTD increases(expression) TRPM4 D008345 CTD decreases(expression) TRPV3 D008345 CTD increases(expression) TSGA10 D008345 CTD increases(expression) TSHZ2 D008345 CTD decreases(expression) TYRP1 D008345 CTD decreases(expression) USP15 D008345 CTD decreases(expression) USP45 D008345 CTD increases(expression) VEGFA D008345 CTD decreases(expression) VPS13A D008345 CTD decreases(expression) WT1 D008345 CTD increases(expression) ZFP41 D008345 CTD increases(expression) ZNF224 D008345
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