DSigDB Home
Search Gene
Collections
Browse Gene Sets
Download
Help

Gene Set: D4 : CTD - Maneb

Collection D4 : CTD
Chemical Name Maneb ( From PubChem : MANEB )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
265.302 g/mol 2 6 0.611 True
Structure
InChI InChI=1S/C4H8N2S4.Mn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-2
InChIKey YKSNLCVSTHTHJA-UHFFFAOYSA-L
Links

Gene (28 / 47)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(cotreatment)BAD
D008344
CTDincreases(phosphorylation)BAD
D008344
CTDaffects(cotreatment)BAX
D008344
CTDincreases(expression)BAX
D008344
CTDaffects(cotreatment)BCL2L1
D008344
CTDdecreases(expression)BCL2L1
D008344
CTDincreases(activity)CASP3
D008344
CTDincreases(activity)CASP7
D008344
CTDincreases(activity)CASP8
D008344
CTDincreases(activity)CASP9
D008344
CTDincreases(expression)GCLC
D008344
CTDaffects(cotreatment)GPX1
D008344
CTDdecreases(response to substance)GPX1
D008344
CTDdecreases(activity)HDAC3
D008344
CTDdecreases(activity)HDAC6
D008344
CTDdecreases(activity)HSD11B2
D008344
CTDaffects(cotreatment)MAPK1
D008344
CTDincreases(phosphorylation)MAPK1
D008344
CTDaffects(cotreatment)MAPK3
D008344
CTDincreases(phosphorylation)MAPK3
D008344
CTDincreases(metabolic processing)MEF2C
D008344
CTDincreases(reaction)MEF2C
D008344
CTDincreases(response to substance)MEF2C
D008344
CTDincreases(expression)NFE2L2
D008344
CTDincreases(expression)NQO1
D008344
CTDincreases(expression)PRDX1
D008344
CTDaffects(activity)PTPN4
D008344
CTDaffects(activity)PTPN9
D008344
CTDdecreases(activity)SIRT1
D008344
CTDdecreases(activity)SIRT2
D008344
CTDdecreases(activity)SIRT3
D008344
CTDaffects(response to substance)SLC6A3
D008344
CTDincreases(reaction)SNCA
D008344
CTDincreases(response to substance)SNCA
D008344
CTDincreases(abundance)SNCA
D008344
CTDincreases(metabolic processing)SNCA
D008344
CTDaffects(cotreatment)SNCA
D008344
CTDincreases(response to substance)SNCA
D008344
CTDaffects(cotreatment)SOD1
D008344
CTDdecreases(response to substance)SOD1
D008344
CTDincreases(expression)TXNRD1
D008344
PubChem Ratio Potency (uM)uM1.860NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM6.859NFE2L2-GI(Protien) :
PubChem PotencyuM27.306NFE2L2-GI(Protien) :
PubChem PotencyuM30.638NFE2L2-GI(Protien) :
PubChem Potency-Replicate_1uM61.131NFE2L2-GI(Protien) :
PubChem NoneuMNR1H4-GI(Protien) :
Download gene sets gmt, text, Detailed text
Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).