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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Lithium

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Collection	D4 : CTD
Chemical Name	Lithium ( From PubChem : LITHIUM )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 6.941 g/mol 0 0 0.0 True
Structure
InChI	InChI=1S/Li
InChIKey	WHXSMMKQMYFTQS-UHFFFAOYSA-N
Links
Gene (56 / 99) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) ADNP2 D008094 CTD increases(expression) AKT1 D008094 CTD increases(phosphorylation) AKT1 D008094 CTD increases(expression) ANTXR2 D008094 CTD decreases(expression) ATM D008094 CTD decreases(reaction) ATP1A1 D008094 CTD increases(expression) ATP1A1 D008094 CTD decreases(reaction) ATP1A2 D008094 CTD increases(expression) ATP1A2 D008094 CTD affects(localization) BAX D008094 CTD decreases(reaction) BAX D008094 CTD affects(binding) BAX D008094 CTD increases(reaction) BAX D008094 CTD decreases(expression) BAX D008094 CTD decreases(expression) BCL2 D008094 CTD decreases(reaction) BCL2 D008094 CTD affects(response to substance) BDNF D008094 CTD increases(response to substance) BDNF D008094 CTD decreases(reaction) CASP3 D008094 CTD increases(activity) CASP3 D008094 CTD decreases(reaction) CASP3 D008094 CTD increases(activity) CASP3 D008094 CTD decreases(reaction) CASP7 D008094 CTD increases(activity) CASP7 D008094 CTD decreases(reaction) CASP8 D008094 CTD increases(activity) CASP8 D008094 CTD decreases(expression) CCND2 D008094 CTD decreases(reaction) CCND2 D008094 CTD increases(expression) CRIP1 D008094 CTD increases(expression) CXCL8 D008094 CTD increases(secretion) CXCL8 D008094 CTD decreases(expression) DDR2 D008094 CTD affects(response to substance) DRD1 D008094 CTD increases(response to substance) DRD1 D008094 CTD increases(expression) DUSP1 D008094 CTD affects(localization) FAS D008094 CTD decreases(reaction) FAS D008094 CTD increases(expression) FAS D008094 CTD increases(expression) FOS D008094 CTD increases(expression) FOSB D008094 CTD increases(phosphorylation) GSK3A D008094 CTD increases(reaction) GSK3A D008094 CTD affects(binding) GSK3B D008094 CTD decreases(reaction) GSK3B D008094 CTD increases(phosphorylation) GSK3B D008094 CTD increases(reaction) GSK3B D008094 CTD increases(phosphorylation) GSK3B D008094 CTD decreases(expression) HILPDA D008094 CTD decreases(expression) HOMER3 D008094 CTD affects(cotreatment) IL1B D008094 CTD decreases(reaction) IL1B D008094 CTD increases(expression) IL1B D008094 CTD affects(expression) KLF6 D008094 CTD increases(activity) MAPK1 D008094 CTD increases(activity) MAPK3 D008094 CTD decreases(reaction) MAPT D008094 CTD increases(phosphorylation) MAPT D008094 CTD decreases(reaction) MIR302B D008094 CTD increases(expression) MIR302B D008094 CTD decreases(reaction) MIR497 D008094 CTD increases(expression) MIR497 D008094 CTD affects(response to substance) NR1D1 D008094 CTD increases(expression) NR4A2 D008094 CTD decreases(reaction) PARP1 D008094 CTD increases(cleavage) PARP1 D008094 CTD increases(expression) PARP4 D008094 CTD increases(expression) PCMT1 D008094 CTD increases(expression) PEX1 D008094 CTD affects(binding) PRKCG D008094 CTD decreases(reaction) PRKCG D008094 CTD decreases(expression) PSMD1 D008094 CTD increases(expression) PTH D008094 CTD increases(activity) RELA D008094 CTD increases(expression) RGCC D008094 CTD increases(expression) RGS2 D008094 CTD increases(expression) RNMT D008094 CTD affects(binding) SCNN1A D008094 CTD increases(transport) SCNN1A D008094 CTD affects(binding) SCNN1B D008094 CTD increases(transport) SCNN1B D008094 CTD affects(binding) SCNN1G D008094 CTD increases(transport) SCNN1G D008094 CTD increases(reaction) SLC13A2 D008094 CTD increases(uptake) SLC13A2 D008094 CTD affects(cotreatment) SLC9A1 D008094 CTD affects(transport) SLC9A1 D008094 CTD decreases(reaction) SLC9A1 D008094 CTD affects(cotreatment) SLC9B2 D008094 CTD affects(transport) SLC9B2 D008094 CTD decreases(expression) STC2 D008094 CTD decreases(expression) SULT1A1 D008094 CTD affects(binding) TP53 D008094 CTD decreases(reaction) TP53 D008094 CTD affects(localization) TP53 D008094 CTD decreases(reaction) TP53 D008094 CTD increases(expression) TP53 D008094 CTD decreases(reaction) TRPM2 D008094 CTD increases(expression) TRPM2 D008094 CTD decreases(expression) VEGFA D008094
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