Tan Lab | DSigDB

Gene Set: D4 : CTD - Lidoflazine

Collection

D4 : CTD

Chemical Name

Lidoflazine ( From PubChem : LIDOFLAZINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
491.615 g/mol	1	4	5.6988	False(3/4)

Structure

InChI

InChI=1S/C30H35F2N3O/c1-22-5-3-6-23(2)30(22)33-29(36)21-35-19-17-34(18-20-35)16-4-7-28(24-8-12-26(31)13-9-24)25-10-14-27(32)15-11-25/h3,5-6,8-15,28H,4,7,16-21H2,1-2H3,(H,33,36)

InChIKey

ZBIAKUMOEKILTF-UHFFFAOYSA-N

Links

Gene (11 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			KCNH2		D008013
CTD	increases(transport)			KCNH2		D008013
CTD	decreases(activity)			KCNH2		D008013
CTD	decreases(reaction)			SLC29A1		D008013
CTD	increases(uptake)			SLC29A1		D008013
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	None	uM		APAF1	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	None	uM		DRD1	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	Potency	uM	5.805	TDP1	-	GI(Protien) :
PubChem	Potency	uM	6.396	TDP1	-	GI(Protien) :
PubChem	Potency	uM	7.308	TDP1	-	GI(Protien) :
ChEMBL	AC50	nM	5011.870	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	5011.900	CYP2D6	-	Target : CHEMBL289

Download gene sets

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