Tan Lab | DSigDB

Gene Set: D4 : CTD - Lidocaine

Collection

D4 : CTD

Chemical Name

Lidocaine ( From PubChem : LIDOCAINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
234.337 g/mol	1	3	2.6567	True

Structure

InChI

InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChIKey

NNJVILVZKWQKPM-UHFFFAOYSA-N

Links

Gene (29 / 57)

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Source	Type	Gene	Other
CTD	decreases(expression)	CASP3	D008012
CTD	increases(activity)	CASP3	D008012
CTD	decreases(expression)	CASP9	D008012
CTD	decreases(reaction)	CCL2	D008012
CTD	increases(expression)	CCL2	D008012
CTD	affects(cotreatment)	CXCL8	D008012
CTD	decreases(expression)	CXCL8	D008012
CTD	affects(metabolic processing)	CYP1A2	D008012
CTD	affects(metabolic processing)	CYP3A4	D008012
CTD	decreases(ethylation)	CYP3A4	D008012
CTD	decreases(methylation)	CYP3A4	D008012
CTD	increases(metabolic processing)	CYP3A4	D008012
CTD	increases(reaction)	CYP3A4	D008012
CTD	decreases(methylation)	CYP3A5	D008012
CTD	increases(expression)	ESR1	D008012
CTD	decreases(expression)	IL6	D008012
CTD	affects(binding)	ITGAM	D008012
CTD	decreases(reaction)	ITGAM	D008012
CTD	increases(expression)	ITGAM	D008012
CTD	affects(binding)	ITGB2	D008012
CTD	decreases(reaction)	ITGB2	D008012
CTD	increases(expression)	ITGB2	D008012
CTD	decreases(activity)	KCNH2	D008012
CTD	decreases(reaction)	KCNK18	D008012
CTD	increases(transport)	KCNK18	D008012
CTD	affects(cotreatment)	KNG1	D008012
CTD	decreases(reaction)	KNG1	D008012
CTD	increases(expression)	KNG1	D008012
CTD	decreases(activity)	KNG1	D008012
CTD	affects(binding)	ORM1	D008012
CTD	decreases(reaction)	ORM1	D008012
CTD	affects(binding)	ORM2	D008012
CTD	decreases(reaction)	ORM2	D008012
CTD	affects(binding)	SCN4A	D008012
CTD	decreases(activity)	SCN4A	D008012
CTD	affects(response to substance)	SCN5A	D008012
CTD	decreases(reaction)	SELL	D008012
CTD	increases(cleavage)	SELL	D008012
CTD	decreases(reaction)	SLC22A1	D008012
CTD	increases(uptake)	SLC22A1	D008012
CTD	decreases(reaction)	SLC22A16	D008012
CTD	increases(uptake)	SLC22A16	D008012
CTD	decreases(reaction)	SLC22A2	D008012
CTD	increases(uptake)	SLC22A2	D008012
CTD	decreases(reaction)	SLC22A3	D008012
CTD	increases(uptake)	SLC22A3	D008012
CTD	decreases(reaction)	SLC22A4	D008012
CTD	increases(uptake)	SLC22A4	D008012
CTD	decreases(reaction)	SLC22A5	D008012
CTD	increases(uptake)	SLC22A5	D008012
CTD	increases(sulfation)	SULT1A1	D008012
CTD	increases(sulfation)	SULT1B1	D008012
CTD	decreases(reaction)	TNF	D008012
CTD	increases(cleavage)	TNF	D008012
CTD	affects(binding)	TNF	D008012
CTD	increases(expression)	TNF	D008012
CTD	increases(activity)	TRPV1	D008012

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