Tan Lab | DSigDB

Gene Set: D4 : CTD - Ketamine

Collection

D4 : CTD

Chemical Name

Ketamine ( From PubChem : KETAMINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	3

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
237.725 g/mol	1	2	3.2887	True

Structure

InChI

InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m0/s1

InChIKey

Links

Gene (19 / 26)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(expression)		AGT		D007649
CTD	decreases(response to substance)		APOE		D007649
CTD	affects(localization)		BAX		D007649
CTD	increases(activity)		CASP3		D007649
CTD	increases(activity)		CASP6		D007649
CTD	increases(activity)		CASP9		D007649
CTD	affects(binding)		CHRM1		D007649
CTD	decreases(reaction)		CHRM1		D007649
CTD	affects(binding)		CHRM2		D007649
CTD	decreases(reaction)		CHRM2		D007649
CTD	affects(binding)		CHRM3		D007649
CTD	decreases(reaction)		CHRM3		D007649
CTD	decreases(activity)		CYP3A4		D007649
CTD	decreases(expression)		CYP3A4		D007649
CTD	decreases(reaction)		IL6		D007649
CTD	increases(expression)		IL6		D007649
CTD	affects(binding)		LBP		D007649
CTD	decreases(reaction)		LBP		D007649
CTD	increases(expression)		MKI67		D007649
CTD	increases(expression)		REN		D007649
CTD	decreases(reaction)		TNF		D007649
CTD	increases(expression)		TNF		D007649
CTD	increases(expression)		TP53		D007649
PubChem	None	uM	TTR	-	GI(Protien) :
ChEMBL	Activity	-	GRIN1	-	Target : CHEMBL1907604
ChEMBL	Activity	-	GRIN2A	-	Target : CHEMBL1907604

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