Tan Lab | DSigDB

Gene Set: D4 : CTD - Isatin

Collection

D4 : CTD

Chemical Name

Isatin ( From PubChem : ISATIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
147.131 g/mol	1	3	0.9594	True

Structure

InChI

InChI=1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)9-8(7)11/h1-4H,(H,9,10,11)

InChIKey

Links

Gene (20 / 33)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(reduction)			AKR1B1		D007510
CTD	increases(reduction)			AKR7A2		D007510
CTD	affects(binding)			CASP3		D007510
CTD	increases(cleavage)			CASP3		D007510
CTD	affects(binding)			CASP9		D007510
CTD	increases(cleavage)			CASP9		D007510
CTD	affects(binding)			CBR1		D007510
CTD	increases(metabolic processing)			CBR1		D007510
CTD	increases(reaction)			CBR1		D007510
CTD	increases(metabolic processing)			CBR3		D007510
CTD	affects(binding)			CDKN1A		D007510
CTD	increases(expression)			CDKN1A		D007510
CTD	decreases(reaction)			CDKN1A		D007510
CTD	affects(binding)			CYCS		D007510
CTD	affects(localization)			CYCS		D007510
CTD	increases(expression)			CYP2A6		D007510
CTD	increases(expression)			CYP2D6		D007510
CTD	increases(expression)			CYP2E1		D007510
CTD	increases(reduction)			DHRS7		D007510
CTD	affects(binding)			SOD1		D007510
CTD	decreases(response to substance)			SOD1		D007510
CTD	affects(binding)			TP53		D007510
CTD	increases(expression)			TP53		D007510
CTD	decreases(reaction)			TP53		D007510
PubChem	AhR Potency (uM)	uM	25.569	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.084	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	35.431	NFE2L2	-	GI(Protien) :
PubChem	None	uM		OPRD1	-	GI(Protien) :
PubChem	None	uM		OPRD1	-	GI(Protien) :
PubChem	None	uM		OPRM1	-	GI(Protien) :
PubChem	None	uM		OPRM1	-	GI(Protien) :
PubChem	None	uM		PECR	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :

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