DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : CTD - Iron

---

Collection	D4 : CTD
Chemical Name	Iron ( From PubChem : IRON )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 55.845 g/mol 0 0 -0.0025 True
Structure
InChI	InChI=1S/Fe
InChIKey	XEEYBQQBJWHFJM-UHFFFAOYSA-N
Links
Gene (180 / 392) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) ACO1 D007501 CTD increases(activity) ACO1 D007501 CTD decreases(reaction) ACO1 D007501 CTD increases(activity) ACO1 D007501 CTD decreases(expression) ADGRG1 D007501 CTD affects(binding) AHSP D007501 CTD affects(folding) AHSP D007501 CTD affects(stability) AHSP D007501 CTD affects(cotreatment) ALB D007501 CTD affects(reaction) ALB D007501 CTD increases(abundance) ALB D007501 CTD decreases(reaction) ALB D007501 CTD decreases(expression) ALDOC D007501 CTD increases(expression) ANKRD22 D007501 CTD increases(expression) ANXA2 D007501 CTD decreases(expression) AP1S3 D007501 CTD increases(response to substance) APOE D007501 CTD increases(expression) APP D007501 CTD increases(uptake) APP D007501 CTD increases(expression) ARID3B D007501 CTD affects(reaction) ARNT D007501 CTD increases(activity) ARNT D007501 CTD increases(expression) ARRDC3 D007501 CTD affects(response to substance) ATM D007501 CTD increases(activity) ATM D007501 CTD increases(phosphorylation) ATM D007501 CTD affects(binding) B2M D007501 CTD decreases(uptake) B2M D007501 CTD affects(cotreatment) BCL2 D007501 CTD decreases(expression) BCL2 D007501 CTD decreases(reaction) BCL2 D007501 CTD affects(cotreatment) BCL2L1 D007501 CTD decreases(expression) BCL2L1 D007501 CTD decreases(reaction) BCL2L1 D007501 CTD increases(expression) BCL3 D007501 CTD increases(expression) CALR D007501 CTD affects(cotreatment) CASP3 D007501 CTD decreases(expression) CASP3 D007501 CTD decreases(reaction) CASP3 D007501 CTD increases(expression) CCL2 D007501 CTD increases(expression) CCL5 D007501 CTD increases(expression) CCNG2 D007501 CTD increases(expression) CCPG1 D007501 CTD increases(expression) CCSAP D007501 CTD increases(expression) CD109 D007501 CTD decreases(reaction) CD14 D007501 CTD increases(expression) CD14 D007501 CTD increases(reaction) CD14 D007501 CTD increases(expression) CD300A D007501 CTD increases(expression) CD58 D007501 CTD increases(expression) CD70 D007501 CTD decreases(expression) CD74 D007501 CTD increases(expression) CDKN2D D007501 CTD increases(expression) CDRT4 D007501 CTD decreases(expression) CHI3L1 D007501 CTD decreases(expression) CLC D007501 CTD increases(expression) CLEC2B D007501 CTD affects(reaction) CP D007501 CTD increases(activity) CP D007501 CTD decreases(export) CP D007501 CTD affects(binding) CP D007501 CTD increases(oxidation) CP D007501 CTD increases(oxidation) CP D007501 CTD increases(stability) CP D007501 CTD decreases(expression) CSTF2T D007501 CTD increases(expression) CXCL8 D007501 CTD decreases(reaction) CXCL8 D007501 CTD increases(expression) CXCL8 D007501 CTD decreases(expression) CXORF21 D007501 CTD decreases(expression) CYBRD1 D007501 CTD increases(expression) CYBRD1 D007501 CTD increases(expression) CYP2A6 D007501 CTD increases(expression) CYTIP D007501 CTD increases(expression) DAXX D007501 CTD decreases(expression) DCANP1 D007501 CTD increases(expression) DDIT3 D007501 CTD decreases(expression) DEFA3 D007501 CTD increases(expression) DOCK10 D007501 CTD decreases(expression) DPY19L2P4 D007501 CTD increases(expression) E2F8 D007501 CTD affects(binding) EGLN1 D007501 CTD decreases(expression) ELANE D007501 CTD increases(expression) EMP1 D007501 CTD decreases(reaction) EPAS1 D007501 CTD increases(expression) EPAS1 D007501 CTD decreases(expression) F13A1 D007501 CTD decreases(activity) F2 D007501 CTD decreases(expression) FAM20C D007501 CTD affects(binding) FEN1 D007501 CTD decreases(reaction) FEN1 D007501 CTD increases(expression) FLOT1 D007501 CTD affects(binding) FTH1 D007501 CTD decreases(expression) FTH1 D007501 CTD increases(abundance) FTH1 D007501 CTD affects(binding) FTL D007501 CTD decreases(reaction) FTL D007501 CTD increases(reaction) FTL D007501 CTD decreases(abundance) FTL D007501 CTD decreases(expression) FTL D007501 CTD increases(abundance) FTL D007501 CTD increases(expression) FTL D007501 CTD decreases(uptake) FTL D007501 CTD affects(binding) FTMT D007501 CTD decreases(reaction) FTMT D007501 CTD increases(reaction) FTMT D007501 CTD increases(abundance) FXN D007501 CTD increases(metabolic processing) FXN D007501 CTD affects(binding) FXN D007501 CTD decreases(abundance) GAS1 D007501 CTD decreases(expression) GAS1 D007501 CTD increases(abundance) GAS1 D007501 CTD increases(expression) GAS1 D007501 CTD increases(expression) GAS7 D007501 CTD decreases(expression) GCLC D007501 CTD decreases(reaction) GCLC D007501 CTD decreases(expression) GCLM D007501 CTD decreases(reaction) GCLM D007501 CTD increases(expression) GPR34 D007501 CTD affects(cotreatment) GSK3B D007501 CTD decreases(activity) GSK3B D007501 CTD decreases(response to substance) GSK3B D007501 CTD decreases(expression) GSS D007501 CTD decreases(reaction) GSS D007501 CTD decreases(secretion) HAMP D007501 CTD increases(expression) HAMP D007501 CTD affects(reaction) HAMP D007501 CTD increases(uptake) HAMP D007501 CTD affects(binding) HBA1 D007501 CTD affects(folding) HBA1 D007501 CTD affects(stability) HBA1 D007501 CTD affects(binding) HDAC8 D007501 CTD increases(activity) HDAC8 D007501 CTD increases(abundance) HFE D007501 CTD increases(uptake) HFE D007501 CTD affects(abundance) HFE D007501 CTD increases(abundance) HFE D007501 CTD affects(abundance) HFE D007501 CTD affects(response to substance) HFE D007501 CTD affects(binding) HFE D007501 CTD decreases(uptake) HFE D007501 CTD affects(binding) HFE D007501 CTD decreases(reaction) HFE D007501 CTD increases(uptake) HFE D007501 CTD decreases(uptake) HFE D007501 CTD increases(reaction) HFE D007501 CTD increases(uptake) HFE D007501 CTD decreases(abundance) HIF1A D007501 CTD increases(expression) HIF1A D007501 CTD decreases(reaction) HIF1A D007501 CTD increases(expression) HIF1A D007501 CTD decreases(reaction) HIF1A D007501 CTD increases(expression) HIF1A D007501 CTD decreases(reaction) HIF1A D007501 CTD increases(stability) HIF1A D007501 CTD affects(localization) HIF1A D007501 CTD decreases(reaction) HIF1A D007501 CTD increases(expression) HIF1A D007501 CTD decreases(abundance) HIF1A D007501 CTD increases(expression) HIF1A D007501 CTD affects(cotreatment) HIST3H3 D007501 CTD decreases(methylation) HIST3H3 D007501 CTD increases(activity) HIST3H3 D007501 CTD increases(methylation) HIST3H3 D007501 CTD increases(abundance) HMOX1 D007501 CTD increases(activity) HMOX1 D007501 CTD increases(expression) HMOX1 D007501 CTD decreases(reaction) HMOX1 D007501 CTD decreases(abundance) HMOX1 D007501 CTD decreases(expression) HMOX1 D007501 CTD increases(abundance) HMOX1 D007501 CTD increases(expression) HMOX1 D007501 CTD increases(abundance) HMOX1 D007501 CTD increases(expression) HMOX1 D007501 CTD increases(degradation) HMOX1 D007501 CTD increases(expression) HMOX1 D007501 CTD increases(reaction) HMOX1 D007501 CTD increases(expression) HPGDS D007501 CTD decreases(expression) HSBP1L1 D007501 CTD decreases(abundance) HSPA1L D007501 CTD decreases(expression) HSPA1L D007501 CTD increases(abundance) HSPA1L D007501 CTD increases(expression) HSPA1L D007501 CTD decreases(abundance) HSPA9 D007501 CTD decreases(expression) HSPA9 D007501 CTD increases(abundance) HSPA9 D007501 CTD increases(expression) HSPA9 D007501 CTD decreases(abundance) HSPH1 D007501 CTD decreases(expression) HSPH1 D007501 CTD increases(abundance) HSPH1 D007501 CTD increases(expression) HSPH1 D007501 CTD affects(abundance) ICAM1 D007501 CTD decreases(reaction) ICAM1 D007501 CTD increases(expression) ICAM1 D007501 CTD affects(binding) IFNG D007501 CTD affects(reaction) IFNG D007501 CTD increases(secretion) IFNG D007501 CTD affects(binding) IL12A D007501 CTD affects(reaction) IL12A D007501 CTD increases(secretion) IL12A D007501 CTD affects(binding) IL12B D007501 CTD affects(reaction) IL12B D007501 CTD increases(secretion) IL12B D007501 CTD affects(reaction) IL18 D007501 CTD increases(secretion) IL18 D007501 CTD decreases(secretion) IL6 D007501 CTD increases(expression) IL6 D007501 CTD increases(expression) IQCD D007501 CTD decreases(expression) IRF8 D007501 CTD increases(expression) ITGAM D007501 CTD increases(reaction) ITGAM D007501 CTD increases(expression) ITGB2 D007501 CTD increases(expression) JAZF1 D007501 CTD decreases(abundance) JUN D007501 CTD increases(expression) JUN D007501 CTD increases(expression) JUN D007501 CTD increases(expression) KDELC1 D007501 CTD affects(cotreatment) KDM3A D007501 CTD decreases(methylation) KDM3A D007501 CTD increases(activity) KDM3A D007501 CTD decreases(expression) KIT D007501 CTD increases(expression) KLHDC7B D007501 CTD decreases(expression) LAMP5 D007501 CTD decreases(activity) LIG3 D007501 CTD decreases(abundance) LOX D007501 CTD increases(expression) LOX D007501 CTD increases(expression) LRRC25 D007501 CTD decreases(expression) LY75 D007501 CTD increases(activity) MAPK1 D007501 CTD increases(phosphorylation) MAPK1 D007501 CTD increases(reaction) MAPK1 D007501 CTD affects(cotreatment) MAPK3 D007501 CTD increases(activity) MAPK3 D007501 CTD increases(phosphorylation) MAPK3 D007501 CTD increases(expression) MCEMP1 D007501 CTD increases(expression) MCTP1 D007501 CTD increases(expression) ME1 D007501 CTD decreases(expression) MIR17HG D007501 CTD increases(abundance) MMP1 D007501 CTD increases(activity) MMP1 D007501 CTD increases(expression) MMP1 D007501 CTD decreases(reaction) MMP1 D007501 CTD decreases(expression) MS4A6A D007501 CTD decreases(abundance) MT2A D007501 CTD increases(expression) MT2A D007501 CTD decreases(abundance) MYC D007501 CTD decreases(expression) MYC D007501 CTD increases(abundance) MYC D007501 CTD increases(expression) MYC D007501 CTD affects(expression) NDUFS1 D007501 CTD affects(binding) NEIL1 D007501 CTD decreases(activity) NEIL1 D007501 CTD decreases(reaction) NEIL1 D007501 CTD affects(folding) NEIL1 D007501 CTD affects(binding) NEIL2 D007501 CTD decreases(activity) NEIL2 D007501 CTD increases(activity) NFE2L2 D007501 CTD increases(expression) NFIL3 D007501 CTD decreases(uptake) NGB D007501 CTD increases(expression) NLRC4 D007501 CTD increases(reduction) NQO1 D007501 CTD decreases(expression) OPN3 D007501 CTD increases(expression) OSBPL11 D007501 CTD increases(expression) P2RX7 D007501 CTD decreases(activity) P4HTM D007501 CTD decreases(reaction) P4HTM D007501 CTD increases(expression) PCGF5 D007501 CTD decreases(abundance) PFKFB4 D007501 CTD increases(expression) PFKFB4 D007501 CTD increases(expression) PIM1 D007501 CTD increases(expression) PIP5K1B D007501 CTD decreases(expression) PLD4 D007501 CTD decreases(abundance) PMP22 D007501 CTD decreases(expression) PMP22 D007501 CTD increases(abundance) PMP22 D007501 CTD increases(expression) PMP22 D007501 CTD increases(expression) PMP22 D007501 CTD affects(binding) POLB D007501 CTD decreases(reaction) POLB D007501 CTD affects(cotreatment) PON1 D007501 CTD decreases(expression) PON1 D007501 CTD decreases(reaction) PON1 D007501 CTD decreases(activity) PON1 D007501 CTD affects(cotreatment) POR D007501 CTD increases(metabolic processing) POR D007501 CTD increases(abundance) POR D007501 CTD increases(expression) PPAP2A D007501 CTD increases(expression) PPARG D007501 CTD increases(expression) PPP1R16B D007501 CTD decreases(expression) PRG3 D007501 CTD decreases(expression) PRTN3 D007501 CTD increases(expression) PTX3 D007501 CTD increases(expression) RELB D007501 CTD increases(expression) RETN D007501 CTD increases(expression) RGS1 D007501 CTD increases(expression) RGS2 D007501 CTD increases(expression) RNASE4 D007501 CTD decreases(expression) ROPN1L D007501 CTD affects(abundance) SELE D007501 CTD decreases(reaction) SELE D007501 CTD increases(expression) SELE D007501 CTD increases(expression) SERPINB8 D007501 CTD decreases(expression) SESN3 D007501 CTD increases(expression) SKA1 D007501 CTD decreases(reaction) SLC11A2 D007501 CTD increases(uptake) SLC11A2 D007501 CTD decreases(abundance) SLC11A2 D007501 CTD increases(expression) SLC11A2 D007501 CTD decreases(reaction) SLC11A2 D007501 CTD increases(uptake) SLC11A2 D007501 CTD affects(binding) SLC11A2 D007501 CTD decreases(uptake) SLC11A2 D007501 CTD decreases(expression) SLC11A2 D007501 CTD increases(expression) SLC11A2 D007501 CTD increases(expression) SLC11A2 D007501 CTD increases(uptake) SLC11A2 D007501 CTD increases(expression) SLC26A11 D007501 CTD increases(expression) SLC2A14 D007501 CTD decreases(expression) SLC2A5 D007501 CTD increases(oxidation) SLC40A1 D007501 CTD increases(stability) SLC40A1 D007501 CTD affects(reaction) SLC40A1 D007501 CTD increases(uptake) SLC40A1 D007501 CTD decreases(expression) SLPI D007501 CTD increases(reaction) SNCA D007501 CTD increases(response to substance) SNCA D007501 CTD affects(localization) SNCA D007501 CTD decreases(reaction) SOD1 D007501 CTD increases(uptake) SOD1 D007501 CTD decreases(activity) SOD2 D007501 CTD decreases(expression) SOD2 D007501 CTD affects(abundance) SOD2 D007501 CTD increases(expression) SORT1 D007501 CTD affects(abundance) SP1 D007501 CTD decreases(reaction) SP1 D007501 CTD increases(activity) SP1 D007501 CTD increases(activity) SRC D007501 CTD increases(phosphorylation) SRC D007501 CTD increases(reaction) SRC D007501 CTD affects(cotreatment) STK11 D007501 CTD affects(reaction) STK11 D007501 CTD decreases(response to substance) STK11 D007501 CTD increases(expression) SULF2 D007501 CTD increases(expression) TES D007501 CTD affects(binding) TF D007501 CTD decreases(uptake) TF D007501 CTD increases(reaction) TF D007501 CTD increases(uptake) TF D007501 CTD decreases(reaction) TF D007501 CTD affects(binding) TF D007501 CTD affects(binding) TF D007501 CTD affects(binding) TF D007501 CTD affects(activity) TF D007501 CTD affects(binding) TF D007501 CTD affects(binding) TF D007501 CTD affects(cotreatment) TF D007501 CTD affects(binding) TF D007501 CTD increases(uptake) TF D007501 CTD affects(binding) TF D007501 CTD affects(transport) TF D007501 CTD affects(binding) TF D007501 CTD affects(binding) TF D007501 CTD increases(uptake) TF D007501 CTD affects(binding) TFR2 D007501 CTD affects(response to substance) TFR2 D007501 CTD decreases(abundance) TFRC D007501 CTD increases(expression) TFRC D007501 CTD decreases(reaction) TFRC D007501 CTD increases(uptake) TFRC D007501 CTD affects(binding) TFRC D007501 CTD increases(expression) TFRC D007501 CTD affects(binding) TFRC D007501 CTD increases(uptake) TFRC D007501 CTD increases(expression) TMEM154 D007501 CTD affects(abundance) TMPRSS6 D007501 CTD affects(abundance) TNF D007501 CTD decreases(reaction) TNF D007501 CTD increases(activity) TNF D007501 CTD increases(expression) TNF D007501 CTD increases(reaction) TNF D007501 CTD increases(uptake) TNF D007501 CTD increases(expression) TNFSF10 D007501 CTD increases(expression) TREML2 D007501 CTD increases(expression) TSHZ3 D007501 CTD affects(binding) TXN2 D007501 CTD increases(oxidation) TXN2 D007501 CTD decreases(expression) UBE2E1 D007501 CTD decreases(activity) UROD D007501 CTD affects(abundance) VCAM1 D007501 CTD decreases(reaction) VCAM1 D007501 CTD increases(expression) VCAM1 D007501 CTD increases(expression) VDR D007501 CTD increases(expression) WIPI1 D007501
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).