DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : CTD - Hydroxychloroquine

---

Collection	D4 : CTD
Chemical Name	Hydroxychloroquine ( From PubChem : HYDROXYCHLOROQUINE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Approved Approved Approved Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 335.872 g/mol 2 4 3.856 True
Structure
InChI	InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)/t14-/m1/s1
InChIKey	XXSMGPRMXLTPCZ-CQSZACIVSA-N
Links
Gene (7 / 13) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(reaction) CASP3 D006886 CTD increases(activity) CASP3 D006886 CTD increases(expression) CCL2 D006886 CTD decreases(expression) CFLAR D006886 CTD increases(expression) CXCL8 D006886 CTD affects(reaction) FAS D006886 CTD increases(activity) FAS D006886 CTD decreases(reaction) IL1B D006886 CTD increases(chemical synthesis) IL1B D006886 CTD increases(expression) IL1B D006886 CTD decreases(reaction) NOS2 D006886 CTD increases(chemical synthesis) NOS2 D006886 CTD increases(expression) NOS2 D006886
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).