Tan Lab | DSigDB

Gene Set: D4 : CTD - Harmaline

Collection

D4 : CTD

Chemical Name

Harmaline ( From PubChem : HARMALINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
214.263 g/mol	1	3	0.4683	True

Structure

InChI

InChI=1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,14H,5-6H2,1-2H3

InChIKey

QJOZJXNKVMFAET-UHFFFAOYSA-N

Links

Gene (21 / 52)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			CCL2		D006246
CTD	increases(expression)			CCL2		D006246
CTD	decreases(reaction)			CXCL8		D006246
CTD	increases(secretion)			CXCL8		D006246
CTD	decreases(reaction)			CXCL8		D006246
CTD	increases(expression)			CXCL8		D006246
CTD	affects(cotreatment)			CYP1A1		D006246
CTD	decreases(expression)			CYP1A1		D006246
CTD	decreases(reaction)			CYP1A1		D006246
CTD	increases(activity)			CYP1A1		D006246
CTD	increases(expression)			CYP1A1		D006246
CTD	decreases(activity)			CYP1A1		D006246
CTD	decreases(stability)			CYP1A1		D006246
CTD	affects(binding)			IL1B		D006246
CTD	decreases(reaction)			IL1B		D006246
CTD	increases(activity)			IL1B		D006246
CTD	increases(secretion)			IL1B		D006246
CTD	affects(binding)			NFKB1		D006246
CTD	decreases(reaction)			NFKB1		D006246
CTD	increases(activity)			NFKB1		D006246
CTD	affects(localization)			NFKB1		D006246
CTD	decreases(reaction)			NFKB1		D006246
CTD	increases(activity)			NFKB1		D006246
CTD	affects(binding)			RELA		D006246
CTD	decreases(reaction)			RELA		D006246
CTD	increases(activity)			RELA		D006246
CTD	affects(localization)			RELA		D006246
CTD	decreases(reaction)			RELA		D006246
CTD	increases(activity)			RELA		D006246
PubChem	None	uM		AHR	-	GI(Protien) :
PubChem	Potency	uM	9.200	ATAD5	-	GI(Protien) :
PubChem	IC50	uM		CBFB	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	15.849	HTT	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
PubChem	None	uM		MAP4K2	-	GI(Protien) :
PubChem	None	uM		PREPL	-	GI(Protien) :
PubChem	None	uM		PSMD14	-	GI(Protien) :
PubChem	IC50	uM		RUNX1	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	9200.000	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	3981.100	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	39810.700	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	15848.900	HTT	-	Target : CHEMBL5514
ChEMBL	Potency	nM	14125.400	RECQL	-	Target : CHEMBL1293236

Download gene sets

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