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Gene Set: D4 : CTD - Halothane

Collection D4 : CTD
Chemical Name Halothane ( From PubChem : HALOTHANE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotApprovedApprovedNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
197.382 g/mol 0 0 2.5085 True
Structure
InChI InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H/t1-/m0/s1
InChIKey BCQZXOMGPXTTIC-SFOWXEAESA-N
Links

Gene (13 / 24)


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Source Type Unit Value Gene PMID Assay Other
CTDaffects(binding)ALB
D006221
CTDincreases(metabolic processing)CYB5A
D006221
CTDincreases(expression)CYB5A
D006221
CTDaffects(metabolic processing)CYP2A6
D006221
CTDincreases(metabolic processing)CYP2A6
D006221
CTDincreases(metabolic processing)CYP2B6
D006221
CTDaffects(metabolic processing)CYP2E1
D006221
CTDincreases(metabolic processing)CYP2E1
D006221
CTDincreases(oxidation)CYP2E1
D006221
CTDdecreases(reaction)CYP2E1
D006221
CTDincreases(metabolic processing)CYP3A4
D006221
CTDincreases(reaction)KCNK10
D006221
CTDincreases(transport)KCNK10
D006221
CTDincreases(reaction)KCNK2
D006221
CTDincreases(transport)KCNK2
D006221
CTDincreases(reaction)KCNK9
D006221
CTDincreases(transport)KCNK9
D006221
CTDdecreases(phosphorylation)PTK2
D006221
CTDaffects(cotreatment)REN
D006221
CTDincreases(activity)REN
D006221
CTDincreases(activity)RYR1
D006221
CTDaffects(localization)RYR1
D006221
CTDincreases(response to substance)RYR1
D006221
ChEMBLPotencynM39810.700HSD17B10
-Target : CHEMBL4159
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