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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Gentamicins

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Collection	D4 : CTD
Chemical Name	Gentamicins ( From PubChem : GENTAMICIN )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Approved Approved Approved Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 477.595 g/mol 8 12 -0.4448 False(2/4)
Structure
InChI	InChI=1S/C21H43N5O7/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20/h9-20,25-29H,5-8,22-24H2,1-4H3
InChIKey	CEAZRRDELHUEMR-UHFFFAOYSA-N
Links
Gene (43 / 77) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(secretion) ANPEP D005839 CTD increases(expression) ARHGEF26 D005839 CTD decreases(expression) ATG3 D005839 CTD increases(expression) ATM D005839 CTD increases(expression) B2M D005839 CTD decreases(reaction) CASP3 D005839 CTD increases(activity) CASP3 D005839 CTD increases(cleavage) CASP3 D005839 CTD increases(activity) CASR D005839 CTD increases(phosphorylation) CASR D005839 CTD increases(reaction) CASR D005839 CTD affects(binding) CASR D005839 CTD decreases(reaction) CCL2 D005839 CTD increases(expression) CCL2 D005839 CTD increases(reaction) CCL2 D005839 CTD increases(activity) CFTR D005839 CTD increases(activity) CFTR D005839 CTD increases(expression) CFTR D005839 CTD affects(cotreatment) CRP D005839 CTD increases(expression) CRP D005839 CTD increases(expression) DMD D005839 CTD increases(expression) EDNRB D005839 CTD increases(expression) F8 D005839 CTD increases(expression) F9 D005839 CTD decreases(expression) GLOD4 D005839 CTD increases(expression) GPR20 D005839 CTD increases(expression) HAX1 D005839 CTD increases(reaction) HAX1 D005839 CTD increases(expression) HLA-F D005839 CTD decreases(reaction) HMOX1 D005839 CTD increases(abundance) HMOX1 D005839 CTD increases(activity) HMOX1 D005839 CTD increases(cleavage) HMOX1 D005839 CTD increases(localization) HMOX1 D005839 CTD increases(expression) HMOX1 D005839 CTD increases(reaction) HMOX1 D005839 CTD increases(expression) HSPA1A D005839 CTD increases(activity) IDUA D005839 CTD increases(expression) IDUA D005839 CTD decreases(abundance) IDUA D005839 CTD increases(expression) IDUA D005839 CTD decreases(expression) IGFBP5 D005839 CTD increases(expression) KCNJ1 D005839 CTD decreases(expression) KCNQ4 D005839 CTD decreases(degradation) LIFR D005839 CTD decreases(expression) LSG1 D005839 CTD decreases(reaction) MAPK1 D005839 CTD increases(activity) MAPK1 D005839 CTD increases(phosphorylation) MAPK1 D005839 CTD increases(reaction) MAPK1 D005839 CTD decreases(reaction) MAPK3 D005839 CTD increases(activity) MAPK3 D005839 CTD increases(phosphorylation) MAPK3 D005839 CTD increases(reaction) MAPK3 D005839 CTD affects(activity) MUT D005839 CTD affects(cotreatment) MUT D005839 CTD affects(expression) MUT D005839 CTD increases(reaction) MUT D005839 CTD decreases(expression) NPRL2 D005839 CTD increases(expression) NT5C2 D005839 CTD decreases(expression) PAIP1 D005839 CTD decreases(expression) PARD3 D005839 CTD decreases(activity) PEPD D005839 CTD decreases(reaction) PEPD D005839 CTD increases(expression) PKD2 D005839 CTD increases(expression) POLM D005839 CTD decreases(reaction) RELA D005839 CTD increases(localization) RELA D005839 CTD decreases(expression) RUNX3 D005839 CTD decreases(expression) SLIT1 D005839 CTD decreases(reaction) TNF D005839 CTD increases(expression) TNF D005839 CTD increases(reaction) TNF D005839 CTD decreases(expression) TNF D005839 CTD increases(expression) TPP1 D005839 CTD increases(expression) USP36 D005839 CTD decreases(expression) ZNF671 D005839
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