DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Fluorides

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Collection	D4 : CTD
Chemical Name	Fluorides ( From PubChem : FLUORIDE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 18.9984 g/mol 0 0 -2.996 True
Structure
InChI	InChI=1S/FH/h1H/p-1
InChIKey	KRHYYFGTRYWZRS-UHFFFAOYSA-M
Links
Gene (55 / 106) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(expression) ATF4 D005459 CTD decreases(activity) BCHE D005459 CTD decreases(reaction) BCHE D005459 CTD decreases(response to substance) BCHE D005459 CTD affects(cotreatment) BIRC3 D005459 CTD decreases(expression) BIRC3 D005459 CTD affects(cotreatment) BIRC5 D005459 CTD increases(expression) BIRC5 D005459 CTD affects(cotreatment) BLK D005459 CTD decreases(expression) BLK D005459 CTD affects(cotreatment) CASP6 D005459 CTD decreases(expression) CASP6 D005459 CTD increases(activity) CAT D005459 CTD increases(reaction) CAT D005459 CTD decreases(activity) CAT D005459 CTD decreases(reaction) CAT D005459 CTD affects(cotreatment) CCL1 D005459 CTD decreases(expression) CCL1 D005459 CTD affects(cotreatment) CCL18 D005459 CTD decreases(expression) CCL18 D005459 CTD affects(cotreatment) CCL19 D005459 CTD decreases(expression) CCL19 D005459 CTD affects(cotreatment) CCL21 D005459 CTD decreases(expression) CCL21 D005459 CTD affects(cotreatment) CCR1 D005459 CTD decreases(expression) CCR1 D005459 CTD affects(cotreatment) CCR2 D005459 CTD decreases(expression) CCR2 D005459 CTD affects(cotreatment) CD40 D005459 CTD increases(expression) CD40 D005459 CTD affects(cotreatment) CD40LG D005459 CTD decreases(expression) CD40LG D005459 CTD affects(cotreatment) CIDEA D005459 CTD decreases(expression) CIDEA D005459 CTD affects(cotreatment) CIDEB D005459 CTD decreases(expression) CIDEB D005459 CTD decreases(expression) CXCL5 D005459 CTD decreases(reaction) CXCL5 D005459 CTD affects(cotreatment) CXCR5 D005459 CTD decreases(expression) CXCR5 D005459 CTD affects(cotreatment) DFFA D005459 CTD decreases(expression) DFFA D005459 CTD affects(cotreatment) DFFB D005459 CTD decreases(expression) DFFB D005459 CTD affects(expression) EIF2AK3 D005459 CTD affects(cotreatment) FASLG D005459 CTD decreases(expression) FASLG D005459 CTD decreases(activity) G6PD D005459 CTD increases(expression) HSPA1A D005459 CTD increases(reaction) HSPA1A D005459 CTD affects(cotreatment) HSPA1A D005459 CTD affects(expression) HSPA5 D005459 CTD affects(cotreatment) IL10RB D005459 CTD decreases(expression) IL10RB D005459 CTD affects(cotreatment) IL11 D005459 CTD increases(expression) IL11 D005459 CTD decreases(expression) IL11 D005459 CTD affects(cotreatment) IL13RA2 D005459 CTD decreases(expression) IL13RA2 D005459 CTD affects(cotreatment) IL18R1 D005459 CTD decreases(expression) IL18R1 D005459 CTD decreases(expression) IL2 D005459 CTD affects(cotreatment) IL2RA D005459 CTD decreases(expression) IL2RA D005459 CTD affects(cotreatment) LTA D005459 CTD decreases(expression) LTA D005459 CTD affects(cotreatment) LTB D005459 CTD decreases(expression) LTB D005459 CTD affects(expression) NFE2L2 D005459 CTD increases(phosphorylation) NOS3 D005459 CTD decreases(reaction) NUDT9 D005459 CTD increases(activity) NUDT9 D005459 CTD increases(expression) RUNX2 D005459 CTD affects(cotreatment) TANK D005459 CTD decreases(expression) TANK D005459 CTD affects(cotreatment) TGFA D005459 CTD decreases(expression) TGFA D005459 CTD affects(cotreatment) TGFB1 D005459 CTD decreases(expression) TGFB1 D005459 CTD affects(cotreatment) TGFB3 D005459 CTD decreases(expression) TGFB3 D005459 CTD affects(cotreatment) TNF D005459 CTD decreases(expression) TNF D005459 CTD affects(cotreatment) TNFRSF10B D005459 CTD increases(expression) TNFRSF10B D005459 CTD increases(expression) TNFRSF11B D005459 CTD affects(cotreatment) TNFRSF14 D005459 CTD decreases(expression) TNFRSF14 D005459 CTD affects(cotreatment) TNFRSF25 D005459 CTD decreases(expression) TNFRSF25 D005459 CTD affects(cotreatment) TNFSF10 D005459 CTD decreases(expression) TNFSF10 D005459 CTD affects(cotreatment) TNFSF11 D005459 CTD decreases(expression) TNFSF11 D005459 CTD affects(expression) TNFSF11 D005459 CTD affects(cotreatment) TNFSF8 D005459 CTD decreases(expression) TNFSF8 D005459 CTD affects(cotreatment) TNFSF9 D005459 CTD decreases(expression) TNFSF9 D005459 CTD affects(cotreatment) TRAF2 D005459 CTD decreases(expression) TRAF2 D005459 CTD affects(cotreatment) TRAF5 D005459 CTD decreases(expression) TRAF5 D005459 CTD affects(expression) XBP1 D005459 CTD affects(cotreatment) XIAP D005459 CTD increases(expression) XIAP D005459
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