Tan Lab | DSigDB

Gene Set: D4 : CTD - Flumazenil

Collection

D4 : CTD

Chemical Name

Flumazenil ( From PubChem : FLUMAZENIL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
303.288 g/mol	0	6	1.7116	True

Structure

InChI

InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3

InChIKey

Links

Gene (9 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			GABRA6		D005442
CTD	increases(activity)			GABRA6		D005442
CTD	increases(reaction)			GABRA6		D005442
CTD	affects(binding)			GABRB3		D005442
CTD	increases(activity)			GABRB3		D005442
CTD	increases(reaction)			GABRB3		D005442
CTD	affects(binding)			GABRG2		D005442
CTD	increases(activity)			GABRG2		D005442
CTD	increases(reaction)			GABRG2		D005442
CTD	decreases(reaction)			SLC22A2		D005442
CTD	increases(uptake)			SLC22A2		D005442
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	1.585	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	None	uM		EIF2AK3	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	2.060	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	7.308	NFE2L2	-	GI(Protien) :
ChEMBL	Potency	nM	1584.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	1584.890	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	2059.600	NFE2L2	-	Target : CHEMBL1075094

Download gene sets