Tan Lab | DSigDB

Gene Set: D4 : CTD - Fenthion

Collection

D4 : CTD

Chemical Name

Fenthion ( From PubChem : FENTHION )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
278.328 g/mol	0	5	4.2636	True

Structure

InChI

InChI=1S/C10H15O3PS2/c1-8-7-9(5-6-10(8)16-4)13-14(15,11-2)12-3/h5-7H,1-4H3

InChIKey

Links

Gene (18 / 28)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ACHE		D005284
CTD	decreases(reaction)			AR		D005284
CTD	increases(activity)			AR		D005284
CTD	decreases(reaction)			AR		D005284
CTD	increases(activity)			AR		D005284
CTD	decreases(activity)			BCHE		D005284
CTD	affects(metabolic processing)			CYP3A4		D005284
CTD	affects(metabolic processing)			CYP3A5		D005284
CTD	affects(metabolic processing)			CYP3A7		D005284
CTD	increases(activity)			ESRRG		D005284
CTD	increases(oxidation)			FMO1		D005284
CTD	increases(expression)			FOS		D005284
CTD	increases(expression)			GADD45A		D005284
CTD	increases(expression)			JUN		D005284
CTD	increases(expression)			MYC		D005284
CTD	increases(expression)			NR4A1		D005284
CTD	increases(expression)			PPP1R15A		D005284
CTD	increases(expression)			SOCS3		D005284
CTD	increases(expression)			TNFAIP3		D005284
PubChem	AhR Potency (uM)	uM	19.950	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.337	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	26.278	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.603	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.296	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	32.712	AHR	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.015	ESR1	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340

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