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Gene Set: D4 : CTD - Fentanyl

Collection D4 : CTD
Chemical Name Fentanyl ( From PubChem : FENTANYL )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotApprovedNot2
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
336.471 g/mol 0 3 4.0746 True
Structure
InChI InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3
InChIKey PJMPHNIQZUBGLI-UHFFFAOYSA-N
Links

Gene (10 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(metabolic processing)CYP3A4
D005283
CTDdecreases(expression)IL2
D005283
CTDincreases(expression)IL4
D005283
CTDincreases(phosphorylation)MAPK1
D005283
CTDincreases(phosphorylation)MAPK3
D005283
CTDincreases(expression)NFKBIA
D005283
CTDincreases(activity)PLD2
D005283
CTDaffects(cotreatment)POMC
D005283
CTDdecreases(expression)POMC
D005283
CTDaffects(cotreatment)REN
D005283
CTDdecreases(expression)REN
D005283
PubChem Potency-Replicate_1uM21.132AR-GI(Protien) :
PubChem Ratio Potency (uM)uM22.148AR-GI(Protien) :
PubChem Potency-Replicate_1uM23.915AR-GI(Protien) :
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