Tan Lab | DSigDB

Gene Set: D4 : CTD - mezerein

Collection

D4 : CTD

Chemical Name

mezerein ( From PubChem : MEZEREIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
654.702 g/mol	3	10	3.1242	False(3/4)

Structure

InChI

InChI=1S/C38H38O10/c1-21(2)36-30(44-27(40)18-12-11-15-24-13-7-5-8-14-24)23(4)37-26-19-22(3)29(41)35(26,43)33(42)34(20-39)31(45-34)28(37)32(36)46-38(47-36,48-37)25-16-9-6-10-17-25/h5-19,23,26,28,30-33,39,42-43H,1,20H2,2-4H3

InChIKey

DLEDLHFNQDHEOJ-UHFFFAOYSA-N

Links

Gene (20 / 29)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			PARP1		C011309
CTD	increases(activity)			PARP1		C011309
CTD	increases(activity)			PARP1		C011309
CTD	affects(cotreatment)			PRKCA		C011309
CTD	decreases(expression)			PRKCA		C011309
CTD	affects(cotreatment)			PRKCB		C011309
CTD	decreases(expression)			PRKCB		C011309
CTD	affects(cotreatment)			PRKCG		C011309
CTD	decreases(expression)			PRKCG		C011309
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	None	uM		CACNA1H	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CHRM1	-	GI(Protien) :
PubChem	None	uM		CRHBP	-	GI(Protien) :
PubChem	None	uM		CRHR2	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		FASN	-	GI(Protien) :
PubChem	Potency	uM	2.818	GLP1R	-	GI(Protien) :
PubChem	None	uM		HTR5A	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	Potency	uM	0.005	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.018	NFE2L2	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	None	uM		SLC6A3	-	GI(Protien) :
PubChem	None	uM		SLC6A3	-	GI(Protien) :
PubChem	None	uM		SLC6A3	-	GI(Protien) :
PubChem	Potency	uM	3.264	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :

Download gene sets

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