Tan Lab | DSigDB

Gene Set: D4 : CTD - Fenbendazole

Collection

D4 : CTD

Chemical Name

Fenbendazole ( From PubChem : FENBENDAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
299.348 g/mol	2	5	3.9654	True

Structure

InChI

InChI=1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChIKey

HDDSHPAODJUKPD-UHFFFAOYSA-N

Links

Gene (24 / 42)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			CCL2		D005273
CTD	increases(expression)			CXCL8		D005273
CTD	increases(secretion)			CXCL8		D005273
CTD	decreases(reaction)			CXCL8		D005273
CTD	decreases(reaction)			GSTP1		D005273
CTD	increases(metabolic processing)			GSTP1		D005273
CTD	increases(expression)			IL6R		D005273
CTD	decreases(expression)			MAPT		D005273
CTD	increases(secretion)			TNF		D005273
CTD	decreases(reaction)			TNF		D005273
CTD	increases(expression)			VEGFA		D005273
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	1.604	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.800	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	6.601	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.688	AHR	-	GI(Protien) :
PubChem	None	uM		APP	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.288	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.422	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.609	AR	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	68.590	ESR1	-	GI(Protien) :
PubChem	Potency	uM	1.122	GLP1R	-	GI(Protien) :
PubChem	Potency	uM	0.640	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.903	GMNN	-	GI(Protien) :
PubChem	Potency	uM	1.158	GMNN	-	GI(Protien) :
PubChem	Potency	uM	2.060	GMNN	-	GI(Protien) :
PubChem	Potency	uM	1.158	IDH1	-	GI(Protien) :
PubChem	None	uM		JAK2	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		PPARD	-	GI(Protien) :
PubChem	None	uM		STAT1	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	0.286	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.360	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.517	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.517	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.651	TDP1	-	GI(Protien) :
PubChem	None	uM		VDR	-	GI(Protien) :
ChEMBL	AC50	nM	794.330	CYP1A2	-	Target : CHEMBL3356

Download gene sets

gmt, text, Detailed text