Tan Lab | DSigDB

Gene Set: D4 : CTD - Eugenol

Collection

D4 : CTD

Chemical Name

Eugenol ( From PubChem : EUGENOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
164.201 g/mol	1	2	2.1293	True

Structure

InChI

InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3

InChIKey

RRAFCDWBNXTKKO-UHFFFAOYSA-N

Links

Gene (161 / 241)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ABCA6		D005054
CTD	affects(localization)			AHR		D005054
CTD	decreases(reaction)			AHR		D005054
CTD	increases(activity)			AHR		D005054
CTD	increases(expression)			AHRR		D005054
CTD	increases(expression)			AKR1B1		D005054
CTD	increases(expression)			AKR1B10		D005054
CTD	increases(expression)			AKR1C1		D005054
CTD	increases(expression)			AKR1C3		D005054
CTD	increases(expression)			ALPL		D005054
CTD	affects(binding)			AR		D005054
CTD	decreases(activity)			AR		D005054
CTD	decreases(expression)			ARHGAP17		D005054
CTD	increases(expression)			ARL4C		D005054
CTD	increases(expression)			ATF3		D005054
CTD	increases(expression)			B2M		D005054
CTD	decreases(expression)			BCL2		D005054
CTD	decreases(expression)			BCL2		D005054
CTD	increases(activity)			BCL2		D005054
CTD	decreases(expression)			BCLAF1		D005054
CTD	increases(expression)			BMP6		D005054
CTD	decreases(expression)			BUB1		D005054
CTD	decreases(expression)			C12ORF4		D005054
CTD	increases(expression)			CALCRL		D005054
CTD	affects(cotreatment)			CAT		D005054
CTD	decreases(reaction)			CAT		D005054
CTD	increases(activity)			CAT		D005054
CTD	increases(expression)			CAT		D005054
CTD	increases(expression)			CCL13		D005054
CTD	increases(expression)			CCL19		D005054
CTD	decreases(expression)			CCL2		D005054
CTD	increases(expression)			CCL2		D005054
CTD	increases(expression)			CCL3		D005054
CTD	increases(expression)			CCL3L1		D005054
CTD	increases(expression)			CCL4		D005054
CTD	increases(expression)			CCL4		D005054
CTD	decreases(expression)			CCR2		D005054
CTD	increases(expression)			CCR5		D005054
CTD	increases(expression)			CCR7		D005054
CTD	decreases(expression)			CD36		D005054
CTD	decreases(activity)			CD86		D005054
CTD	decreases(reaction)			CD86		D005054
CTD	increases(expression)			CD86		D005054
CTD	increases(expression)			CD86		D005054
CTD	decreases(expression)			CDK6		D005054
CTD	increases(expression)			CDKN1B		D005054
CTD	affects(expression)			CREB1		D005054
CTD	increases(expression)			CREM		D005054
CTD	increases(expression)			CTSL		D005054
CTD	increases(expression)			CXCL1		D005054
CTD	decreases(reaction)			CXCL8		D005054
CTD	increases(expression)			CXCL8		D005054
CTD	increases(expression)			CXCL8		D005054
CTD	increases(expression)			CXCR4		D005054
CTD	affects(cotreatment)			CYP1A1		D005054
CTD	increases(activity)			CYP1A1		D005054
CTD	decreases(reaction)			CYP1A1		D005054
CTD	increases(expression)			CYP1A1		D005054
CTD	increases(activity)			CYP1A1		D005054
CTD	increases(metabolic processing)			CYP1A1		D005054
CTD	decreases(activity)			CYP1A1		D005054
CTD	decreases(expression)			CYP1A1		D005054
CTD	increases(expression)			CYP1A1		D005054
CTD	affects(cotreatment)			CYP1A2		D005054
CTD	increases(activity)			CYP1A2		D005054
CTD	decreases(reaction)			CYP1B1		D005054
CTD	increases(expression)			CYP1B1		D005054
CTD	increases(activity)			CYP1B1		D005054
CTD	increases(metabolic processing)			CYP1B1		D005054
CTD	decreases(activity)			CYP1B1		D005054
CTD	decreases(expression)			CYP27A1		D005054
CTD	affects(cotreatment)			CYP2C9		D005054
CTD	increases(activity)			CYP2C9		D005054
CTD	affects(cotreatment)			CYP2D6		D005054
CTD	decreases(reaction)			CYP2D6		D005054
CTD	increases(activity)			CYP2D6		D005054
CTD	increases(metabolic processing)			CYP2D6		D005054
CTD	increases(abundance)			CYP2D6		D005054
CTD	affects(cotreatment)			CYP2E1		D005054
CTD	increases(activity)			CYP2E1		D005054
CTD	decreases(expression)			DKC1		D005054
CTD	decreases(expression)			DLGAP5		D005054
CTD	increases(expression)			DNAJB4		D005054
CTD	decreases(expression)			E2F1		D005054
CTD	decreases(expression)			E2F2		D005054
CTD	decreases(expression)			E2F3		D005054
CTD	decreases(expression)			E2F4		D005054
CTD	decreases(expression)			E2F5		D005054
CTD	increases(expression)			E2F6		D005054
CTD	decreases(expression)			EGR2		D005054
CTD	decreases(expression)			EMB		D005054
CTD	affects(binding)			ESR1		D005054
CTD	decreases(reaction)			ESR1		D005054
CTD	affects(binding)			ESR2		D005054
CTD	decreases(reaction)			ESR2		D005054
CTD	decreases(expression)			F13A1		D005054
CTD	decreases(expression)			FBXO9		D005054
CTD	increases(expression)			FCGR2B		D005054
CTD	increases(expression)			FECH		D005054
CTD	increases(expression)			FOSL2		D005054
CTD	increases(expression)			FTL		D005054
CTD	increases(expression)			G6PD		D005054
CTD	increases(expression)			GCLC		D005054
CTD	increases(expression)			GCLM		D005054
CTD	increases(expression)			GLYCAM1		D005054
CTD	increases(expression)			GPX3		D005054
CTD	increases(expression)			GSK3B		D005054
CTD	increases(expression)			GSR		D005054
CTD	decreases(activity)			GSTA1		D005054
CTD	decreases(activity)			GSTM1		D005054
CTD	decreases(activity)			GSTP1		D005054
CTD	decreases(expression)			GYPB		D005054
CTD	decreases(expression)			HEATR5B		D005054
CTD	increases(expression)			HIF1A		D005054
CTD	increases(expression)			HLA-B		D005054
CTD	increases(expression)			HMOX1		D005054
CTD	decreases(expression)			HNRNPA3		D005054
CTD	increases(expression)			HSPA6		D005054
CTD	increases(expression)			HSPH1		D005054
CTD	decreases(expression)			IBSP		D005054
CTD	decreases(expression)			IDI1		D005054
CTD	affects(cotreatment)			IL1B		D005054
CTD	decreases(reaction)			IL1B		D005054
CTD	increases(secretion)			IL1B		D005054
CTD	decreases(reaction)			IL1B		D005054
CTD	increases(expression)			IL1B		D005054
CTD	increases(secretion)			IL1B		D005054
CTD	decreases(expression)			IL1B		D005054
CTD	decreases(expression)			IL1B		D005054
CTD	increases(activity)			IL1B		D005054
CTD	increases(expression)			IL1B		D005054
CTD	increases(expression)			IL1R2		D005054
CTD	increases(expression)			IL7R		D005054
CTD	decreases(expression)			IPCEF1		D005054
CTD	increases(expression)			ITGA6		D005054
CTD	increases(expression)			ITGB1		D005054
CTD	decreases(activity)			KCNA5		D005054
CTD	decreases(expression)			KCNJ2		D005054
CTD	decreases(expression)			KIF23		D005054
CTD	increases(expression)			MAFF		D005054
CTD	increases(expression)			MAFG		D005054
CTD	increases(expression)			MAFK		D005054
CTD	decreases(expression)			MCTS1		D005054
CTD	increases(expression)			ME1		D005054
CTD	increases(expression)			MGST1		D005054
CTD	decreases(expression)			MRPL35		D005054
CTD	increases(expression)			MS4A7		D005054
CTD	increases(expression)			MT1X		D005054
CTD	increases(expression)			MXD1		D005054
CTD	decreases(expression)			MYB		D005054
CTD	increases(expression)			NAMPT		D005054
CTD	affects(expression)			NFE2L2		D005054
CTD	increases(expression)			NFE2L2		D005054
CTD	increases(reaction)			NFE2L2		D005054
CTD	affects(expression)			NFKB1		D005054
CTD	affects(binding)			NFKB1		D005054
CTD	decreases(reaction)			NFKB1		D005054
CTD	increases(activity)			NFKB1		D005054
CTD	decreases(activity)			NQO1		D005054
CTD	decreases(reaction)			NQO1		D005054
CTD	increases(expression)			NQO1		D005054
CTD	increases(expression)			NQO1		D005054
CTD	increases(reaction)			NQO1		D005054
CTD	increases(activity)			NQO1		D005054
CTD	increases(expression)			NQO1		D005054
CTD	increases(expression)			NUP88		D005054
CTD	decreases(expression)			PAICS		D005054
CTD	increases(expression)			PDE4B		D005054
CTD	increases(expression)			PGD		D005054
CTD	increases(expression)			PICALM		D005054
CTD	increases(expression)			PLAT		D005054
CTD	increases(expression)			PMAIP1		D005054
CTD	affects(binding)			PPARG		D005054
CTD	increases(activity)			PPARG		D005054
CTD	decreases(expression)			PRDX3		D005054
CTD	decreases(expression)			PTGER3		D005054
CTD	increases(expression)			PTGR1		D005054
CTD	affects(cotreatment)			PTGS2		D005054
CTD	decreases(reaction)			PTGS2		D005054
CTD	increases(expression)			PTGS2		D005054
CTD	decreases(reaction)			PTGS2		D005054
CTD	increases(expression)			PTGS2		D005054
CTD	decreases(expression)			PTGS2		D005054
CTD	decreases(expression)			RB1		D005054
CTD	affects(binding)			RELA		D005054
CTD	decreases(reaction)			RELA		D005054
CTD	increases(activity)			RELA		D005054
CTD	increases(expression)			RGS1		D005054
CTD	increases(expression)			RPL27A		D005054
CTD	increases(expression)			RRM2B		D005054
CTD	increases(expression)			SAT1		D005054
CTD	increases(expression)			SDC2		D005054
CTD	decreases(expression)			SEPT11		D005054
CTD	decreases(expression)			SLAMF1		D005054
CTD	increases(expression)			SLC16A10		D005054
CTD	increases(expression)			SLC2A3		D005054
CTD	decreases(expression)			SOD1		D005054
CTD	increases(reaction)			SOD1		D005054
CTD	increases(expression)			SOD1		D005054
CTD	decreases(expression)			SOD2		D005054
CTD	increases(reaction)			SOD2		D005054
CTD	increases(expression)			SOD2		D005054
CTD	increases(expression)			SOD3		D005054
CTD	increases(expression)			SRXN1		D005054
CTD	decreases(expression)			STAT1		D005054
CTD	increases(expression)			STAT4		D005054
CTD	increases(expression)			STAT5B		D005054
CTD	increases(expression)			TLR4		D005054
CTD	affects(expression)			TNF		D005054
CTD	affects(cotreatment)			TNF		D005054
CTD	decreases(reaction)			TNF		D005054
CTD	increases(secretion)			TNF		D005054
CTD	decreases(reaction)			TNF		D005054
CTD	increases(expression)			TNF		D005054
CTD	increases(secretion)			TNF		D005054
CTD	affects(binding)			TNF		D005054
CTD	decreases(reaction)			TNF		D005054
CTD	increases(activity)			TNF		D005054
CTD	increases(expression)			TNFAIP3		D005054
CTD	increases(expression)			TNFAIP6		D005054
CTD	increases(mutagenesis)			TP53		D005054
CTD	decreases(expression)			TP63		D005054
CTD	affects(binding)			TRPV3		D005054
CTD	increases(activity)			TRPV3		D005054
CTD	increases(expression)			TXN2		D005054
CTD	increases(expression)			TXNRD1		D005054
CTD	increases(expression)			TXNRD2		D005054
CTD	increases(expression)			UGDH		D005054
CTD	increases(glucuronidation)			UGT1A1		D005054
CTD	increases(glucuronidation)			UGT1A10		D005054
CTD	increases(expression)			UGT1A6		D005054
CTD	increases(glucuronidation)			UGT1A7		D005054
CTD	increases(glucuronidation)			UGT1A8		D005054
CTD	increases(glucuronidation)			UGT1A9		D005054
CTD	increases(metabolic processing)			UGT2B15		D005054
CTD	increases(metabolic processing)			UGT2B15		D005054
CTD	increases(metabolic processing)			UGT2B17		D005054
CTD	increases(expression)			VDR		D005054
CTD	decreases(expression)			ZBTB17		D005054
PubChem	Potency	uM	14.125	ALDH1A1	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	ALDH1A1	-	Target : CHEMBL3577

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