Tan Lab | DSigDB

Gene Set: D4 : CTD - Etazolate

Collection

D4 : CTD

Chemical Name

Etazolate ( From PubChem : ETAZOLATE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
289.333 g/mol	1	7	2.5086	True

Structure

InChI

InChI=1S/C14H19N5O2/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2/h7-8H,5-6H2,1-4H3,(H,15,18)

InChIKey

Links

Gene (8 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			IL13		D004974
CTD	decreases(secretion)			IL13		D004974
CTD	decreases(secretion)			LTC4S		D004974
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	15.849	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	29.935	EHMT2	-	GI(Protien) :
PubChem	None	uM		PDE4B	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	11.005	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	29.849	AHR	-	GI(Protien) :
ChEMBL	Potency	nM	3162.300	CREBBP	-	Target : CHEMBL5747
ChEMBL	AC50	nM	125.890	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	501.190	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	12589.200	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	15848.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	29934.900	EHMT2	-	Target : CHEMBL6032

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