Tan Lab | DSigDB

Gene Set: D4 : CTD - Estriol

Collection

D4 : CTD

Chemical Name

Estriol ( From PubChem : ESTRIOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
288.381 g/mol	3	3	2.58	True

Structure

InChI

InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1

InChIKey

PROQIPRRNZUXQM-ZXXIGWHRSA-N

Links

Gene (49 / 92)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(export)			ABCB1		D004964
CTD	decreases(reaction)			ABCB1		D004964
CTD	increases(expression)			ABCB1		D004964
CTD	increases(expression)			ABCG2		D004964
CTD	increases(expression)			ABCG2		D004964
CTD	decreases(reaction)			ABCG2		D004964
CTD	affects(expression)			ACTC1		D004964
CTD	increases(expression)			AFP		D004964
CTD	increases(expression)			AGER		D004964
CTD	decreases(expression)			AGTR1		D004964
CTD	decreases(reaction)			AR		D004964
CTD	increases(activity)			AR		D004964
CTD	decreases(expression)			ARHGDIA		D004964
CTD	increases(expression)			B4GALT1		D004964
CTD	decreases(reaction)			CCNE1		D004964
CTD	increases(cleavage)			CCNE1		D004964
CTD	decreases(reaction)			CYP19A1		D004964
CTD	increases(expression)			CYP19A1		D004964
CTD	decreases(expression)			CYP19A1		D004964
CTD	increases(expression)			EGR3		D004964
CTD	decreases(expression)			ENO2		D004964
CTD	affects(binding)			ESR1		D004964
CTD	increases(activity)			ESR1		D004964
CTD	affects(binding)			ESR1		D004964
CTD	affects(binding)			ESR1		D004964
CTD	decreases(reaction)			ESR1		D004964
CTD	affects(binding)			ESR1		D004964
CTD	decreases(reaction)			ESR1		D004964
CTD	affects(binding)			ESR1		D004964
CTD	increases(reaction)			ESR1		D004964
CTD	increases(activity)			ESR1		D004964
CTD	increases(expression)			ESR1		D004964
CTD	decreases(reaction)			ESR1		D004964
CTD	affects(binding)			ESR2		D004964
CTD	increases(activity)			ESR2		D004964
CTD	affects(binding)			ESR2		D004964
CTD	affects(binding)			ESR2		D004964
CTD	decreases(reaction)			ESR2		D004964
CTD	increases(expression)			F10		D004964
CTD	increases(expression)			FAM102A		D004964
CTD	increases(expression)			FOXA2		D004964
CTD	decreases(expression)			HNF4A		D004964
CTD	increases(expression)			IGF1		D004964
CTD	decreases(expression)			IGFBP5		D004964
CTD	decreases(expression)			IL1A		D004964
CTD	decreases(expression)			IL6		D004964
CTD	increases(expression)			NOS3		D004964
CTD	decreases(expression)			PDGFA		D004964
CTD	increases(expression)			PDZK1		D004964
CTD	increases(expression)			PGR		D004964
CTD	affects(localization)			RELA		D004964
CTD	decreases(reaction)			RELA		D004964
CTD	decreases(expression)			SELENBP1		D004964
CTD	decreases(expression)			SLC12A2		D004964
CTD	increases(expression)			SLC7A11		D004964
CTD	decreases(activity)			SULT1E1		D004964
CTD	decreases(abundance)			TBX19		D004964
CTD	increases(expression)			TFF1		D004964
CTD	decreases(reaction)			TFF1		D004964
CTD	affects(localization)			TNF		D004964
CTD	decreases(reaction)			TNF		D004964
CTD	increases(expression)			TNF		D004964
CTD	increases(glucuronidation)			UGT1A1		D004964
CTD	increases(glucuronidation)			UGT1A10		D004964
CTD	increases(glucuronidation)			UGT1A3		D004964
CTD	increases(glucuronidation)			UGT1A7		D004964
CTD	increases(glucuronidation)			UGT1A8		D004964
CTD	increases(glucuronidation)			UGT2B11		D004964
CTD	increases(glucuronidation)			UGT2B15		D004964
CTD	increases(metabolic processing)			UGT2B15		D004964
CTD	increases(glucuronidation)			UGT2B4		D004964
CTD	increases(glucuronidation)			UGT2B7		D004964
CTD	increases(glucuronidation)			UGT2B7		D004964
CTD	decreases(reaction)			VCAM1		D004964
CTD	increases(expression)			VCAM1		D004964
CTD	increases(expression)			VDR		D004964
CTD	increases(expression)			WARS		D004964
PubChem	Potency-Replicate_1	uM	6.917	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.801	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	18.996	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	20.122	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	54.483	AR	-	GI(Protien) :
PubChem	None	uM		CACNA1H	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.001	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.002	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.002	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.002	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.004	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM		ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.986	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	38.895	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :

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