Tan Lab | DSigDB

Gene Set: D4 : CTD - Epinephrine

Collection

D4 : CTD

Chemical Name

Epinephrine ( From PubChem : EPINEPHRINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
183.204 g/mol	4	4	0.7415	True

Structure

InChI

InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChIKey

UCTWMZQNUQWSLP-VIFPVBQESA-N

Links

Gene (48 / 144)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			ADRA1A		D004837
CTD	increases(abundance)			ADRA1A		D004837
CTD	increases(activity)			ADRA1A		D004837
CTD	affects(binding)			ADRA1A		D004837
CTD	affects(binding)			ADRA1A		D004837
CTD	increases(activity)			ADRA1A		D004837
CTD	increases(abundance)			ADRA1A		D004837
CTD	decreases(reaction)			ADRA1A		D004837
CTD	decreases(reaction)			ADRA1B		D004837
CTD	increases(abundance)			ADRA1B		D004837
CTD	increases(activity)			ADRA1B		D004837
CTD	affects(binding)			ADRA1B		D004837
CTD	increases(activity)			ADRA1B		D004837
CTD	increases(abundance)			ADRA1B		D004837
CTD	decreases(reaction)			ADRA1B		D004837
CTD	decreases(reaction)			ADRA1D		D004837
CTD	increases(abundance)			ADRA1D		D004837
CTD	increases(activity)			ADRA1D		D004837
CTD	affects(binding)			ADRA1D		D004837
CTD	affects(binding)			ADRA1D		D004837
CTD	increases(activity)			ADRA1D		D004837
CTD	increases(abundance)			ADRA1D		D004837
CTD	decreases(reaction)			ADRA1D		D004837
CTD	affects(binding)			ADRA2A		D004837
CTD	increases(activity)			ADRA2A		D004837
CTD	increases(abundance)			ADRA2A		D004837
CTD	decreases(reaction)			ADRA2A		D004837
CTD	affects(binding)			ADRA2B		D004837
CTD	increases(activity)			ADRA2B		D004837
CTD	increases(abundance)			ADRA2B		D004837
CTD	decreases(reaction)			ADRA2B		D004837
CTD	affects(binding)			ADRA2C		D004837
CTD	increases(activity)			ADRA2C		D004837
CTD	increases(abundance)			ADRA2C		D004837
CTD	decreases(reaction)			ADRA2C		D004837
CTD	affects(binding)			ADRB1		D004837
CTD	increases(activity)			ADRB1		D004837
CTD	increases(abundance)			ADRB1		D004837
CTD	decreases(reaction)			ADRB1		D004837
CTD	affects(binding)			ADRB1		D004837
CTD	decreases(reaction)			ADRB1		D004837
CTD	affects(binding)			ADRB2		D004837
CTD	decreases(reaction)			ADRB2		D004837
CTD	increases(activity)			ADRB2		D004837
CTD	increases(abundance)			ADRB2		D004837
CTD	affects(binding)			ADRB2		D004837
CTD	decreases(reaction)			ADRB2		D004837
CTD	increases(activity)			ADRB2		D004837
CTD	affects(binding)			ADRB2		D004837
CTD	increases(activity)			ADRB2		D004837
CTD	increases(abundance)			ADRB2		D004837
CTD	affects(binding)			ADRB2		D004837
CTD	decreases(reaction)			ADRB2		D004837
CTD	increases(phosphorylation)			ADRB2		D004837
CTD	increases(reaction)			ADRB2		D004837
CTD	increases(activity)			ADRB2		D004837
CTD	increases(localization)			ADRB2		D004837
CTD	affects(binding)			ADRB3		D004837
CTD	increases(activity)			ADRB3		D004837
CTD	affects(binding)			ADRB3		D004837
CTD	increases(abundance)			ADRB3		D004837
CTD	increases(activity)			ADRB3		D004837
CTD	decreases(reaction)			ADRB3		D004837
CTD	increases(phosphorylation)			ADRBK1		D004837
CTD	increases(reaction)			ADRBK1		D004837
CTD	increases(expression)			CA2		D004837
CTD	decreases(reaction)			CASP3		D004837
CTD	increases(activity)			CASP3		D004837
CTD	decreases(reaction)			CCL3		D004837
CTD	increases(expression)			CCL3		D004837
CTD	affects(binding)			CHRNA7		D004837
CTD	decreases(activity)			CHRNA7		D004837
CTD	decreases(reaction)			CHRNA7		D004837
CTD	increases(abundance)			CHRNA7		D004837
CTD	increases(methylation)			COMT		D004837
CTD	decreases(activity)			COMT		D004837
CTD	increases(abundance)			COMT		D004837
CTD	increases(expression)			CTSK		D004837
CTD	decreases(reaction)			FAS		D004837
CTD	increases(expression)			FAS		D004837
CTD	decreases(reaction)			FASLG		D004837
CTD	increases(expression)			FASLG		D004837
CTD	increases(phosphorylation)			GRK5		D004837
CTD	increases(reaction)			GRK5		D004837
CTD	increases(expression)			IL10		D004837
CTD	increases(reaction)			IL10		D004837
CTD	decreases(reaction)			IL1B		D004837
CTD	increases(expression)			IL1B		D004837
CTD	decreases(reaction)			IL6		D004837
CTD	increases(expression)			IL6		D004837
CTD	decreases(expression)			INS		D004837
CTD	decreases(reaction)			INS		D004837
CTD	decreases(expression)			INS		D004837
CTD	decreases(reaction)			INS		D004837
CTD	decreases(secretion)			INS		D004837
CTD	affects(cotreatment)			ITGA2		D004837
CTD	affects(response to substance)			ITGA2		D004837
CTD	increases(expression)			ITGAV		D004837
CTD	increases(activity)			LIPE		D004837
CTD	decreases(reaction)			LIPE		D004837
CTD	decreases(phosphorylation)			MAPK1		D004837
CTD	decreases(reaction)			MAPK1		D004837
CTD	decreases(phosphorylation)			MAPK3		D004837
CTD	decreases(reaction)			MAPK3		D004837
CTD	decreases(activity)			P2RX7		D004837
CTD	increases(activity)			REN		D004837
CTD	decreases(reaction)			REN		D004837
CTD	increases(activity)			REN		D004837
CTD	decreases(reaction)			SOD1		D004837
CTD	increases(activity)			SOD1		D004837
CTD	increases(expression)			SOD1		D004837
CTD	decreases(reaction)			SOD2		D004837
CTD	increases(activity)			SOD2		D004837
CTD	increases(expression)			SOD2		D004837
CTD	increases(sulfation)			SULT1A3		D004837
CTD	decreases(reaction)			TNF		D004837
CTD	increases(expression)			TNF		D004837
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	0.164	DRD1	-	GI(Protien) :
PubChem	Potency	uM	2.512	DRD1	-	GI(Protien) :
PubChem	Potency	uM	10.621	FEN1	-	GI(Protien) :
PubChem	Potency	uM	10.621	FEN1	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	1.585	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	7.943	MAPT	-	GI(Protien) :
PubChem	Potency	uM	12.589	MAPT	-	GI(Protien) :
PubChem	Potency	uM	14.125	MAPT	-	GI(Protien) :
PubChem	Potency	uM	26.122	MTOR	-	GI(Protien) :
PubChem	Potency	uM	48.558	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.995	POLK	-	GI(Protien) :
PubChem	Potency	uM	2.668	POLK	-	GI(Protien) :
PubChem	Potency	uM	7.080	POLK	-	GI(Protien) :
PubChem	Potency	uM	8.414	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.886	TDP1	-	GI(Protien) :
PubChem	Potency	uM	31.623	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	2511.900	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	10621.300	FEN1	-	Target : CHEMBL5027
ChEMBL	Potency	nM	1584.900	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	794.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	7079.500	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	7943.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	26121.600	MTOR	-	Target : CHEMBL2842
ChEMBL	Potency	nM	17782.800	RECQL	-	Target : CHEMBL1293236

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